Peking University Health Science Center, 38 Huayuan Road, Haidian District, Beijing 100191, China; School of Nursing, Peking University, Beijing, China.
Peking University Health Science Center, 38 Huayuan Road, Haidian District, Beijing 100191, China; School of Nursing, Peking University, Beijing, China.
Diabetes Res Clin Pract. 2024 Nov;217:111863. doi: 10.1016/j.diabres.2024.111863. Epub 2024 Sep 19.
To determine the prevalence and patterns of diabetes distress, and evaluate the differences in health outcomes between profiles.
This cross-sectional study included 330 adults with T2DM and overweight/obesity. The participants completed questionnaires on diabetes distress, sleep quality, self-efficacy, depression, anxiety and positive and negative affect. A cluster analysis was performed to identify different patterns of diabetes distress and one-way ANOVA was used to investigate the differences in physical and psychological outcomes between profiles.
30.6% of patients were identified as moderately to highly distressed, with the regimen-related distress found to be the most prominent. The Cluster analysis revealed four distinct clusters: (1) "comprehensively exhausted profile"; (2) "strained profile"; (3) "high internal anguish profile"; (4) "unperturbed profile". The measures of fasting blood glucose (FBG), glycated hemoglobin (HbA1c), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, sleep quality, depression, anxiety, positive and negative affect and self-efficacy differ between clusters.
This study identified important differences that existed in patterns of diabetes distress among people with T2DM and overweight/obesity, and this variation can be utilized to tailor intervention strategies to the particular needs of different subgroups within individuals with T2DM.
确定糖尿病困扰的患病率和模式,并评估不同特征人群的健康结果差异。
本横断面研究纳入了 330 名 T2DM 合并超重/肥胖的成年人。参与者完成了关于糖尿病困扰、睡眠质量、自我效能、抑郁、焦虑以及正性和负性情绪的问卷。采用聚类分析来确定不同的糖尿病困扰模式,并采用单因素方差分析来研究不同特征人群在生理和心理结果方面的差异。
30.6%的患者被认为存在中度至高度困扰,其中与治疗方案相关的困扰最为突出。聚类分析揭示了四个不同的特征人群:(1)“全面疲惫特征人群”;(2)“紧张特征人群”;(3)“高度内心痛苦特征人群”;(4)“无困扰特征人群”。空腹血糖(FBG)、糖化血红蛋白(HbA1c)、低密度脂蛋白(LDL)胆固醇、高密度脂蛋白(HDL)胆固醇、睡眠质量、抑郁、焦虑、正性和负性情绪以及自我效能等指标在不同特征人群之间存在差异。
本研究在 T2DM 合并超重/肥胖患者中发现了糖尿病困扰模式的重要差异,这种差异可用于根据个体内不同亚组的特定需求来定制干预策略。