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Glucocorticoids in Acute Spinal Cord Injury: Why are they still used nowadays?

作者信息

Zarra Francisco, Rolando Marcos, Gandhi Dhruv Nihal, Alozai Muhammad Ilyas, Mercado Alejandro, Chaurasia Bipin, Videtta Walter

机构信息

Department of Neurosurgery, University of Buenos Aires School of Medicine, Buenos Aires, Argentina.

Department of Intensive Care Unit, Clínica la Sagrada Familia, Ciudad Autónoma de Buenos Aires, Argentina.

出版信息

Neurosurg Rev. 2024 Sep 21;47(1):658. doi: 10.1007/s10143-024-02900-4.

DOI:10.1007/s10143-024-02900-4
PMID:39304573
Abstract
摘要

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Glucocorticoids in Acute Spinal Cord Injury: Why are they still used nowadays?急性脊髓损伤中的糖皮质激素:为何如今仍在使用?
Neurosurg Rev. 2024 Sep 21;47(1):658. doi: 10.1007/s10143-024-02900-4.
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Acute adrenal insufficiency after large-dose glucocorticoids for spinal cord injury.大剂量糖皮质激素治疗脊髓损伤后急性肾上腺皮质功能不全
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Glucocorticoid therapy of spinal cord injury.脊髓损伤的糖皮质激素治疗。
Ann N Y Acad Sci. 1994 Nov 14;743:241-63; discussion 263-5. doi: 10.1111/j.1749-6632.1994.tb55796.x.
4
Glucocorticoid mechanisms in acute spinal cord injury: a review and therapeutic rationale.急性脊髓损伤中的糖皮质激素机制:综述与治疗原理
Surg Neurol. 1982 Nov;18(5):320-7. doi: 10.1016/0090-3019(82)90140-9.
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Questionnaire survey of the views of the delegates at the European Cervical Spine Research Society meeting on the administration of methylprednisolone for acute traumatic spinal cord injury.关于欧洲颈椎研究学会会议代表对甲基强的松龙用于急性创伤性脊髓损伤治疗的观点的问卷调查
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[Current role of methylprednisolone in the treatment of acute spinal cord injury].[甲泼尼龙在急性脊髓损伤治疗中的当前作用]
Acta Chir Orthop Traumatol Cech. 2011;78(4):305-13.
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Glucocorticoid-induced leucine zipper (GILZ) controls inflammation and tissue damage after spinal cord injury.糖皮质激素诱导亮氨酸拉链蛋白(GILZ)可控制脊髓损伤后的炎症反应和组织损伤。
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Use of high-dose glucocorticoids in acute head and spinal cord injuries.大剂量糖皮质激素在急性颅脑和脊髓损伤中的应用。
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Role of glucocorticosteroids in treatment of acute spinal cord injury.糖皮质激素在急性脊髓损伤治疗中的作用。
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Steroids for acute spinal cord injury.用于急性脊髓损伤的类固醇。
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The Prevalence of Adrenal Insufficiency in Individuals with Traumatic Spinal Cord Injury: A Systematic Review and Meta-Analysis.创伤性脊髓损伤患者肾上腺功能不全的患病率:一项系统评价和荟萃分析。
J Clin Med. 2025 Mar 21;14(7):2141. doi: 10.3390/jcm14072141.
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Outcomes of non-limited versus cranial-limited extensive hemilaminectomy and durotomy in dogs with thoracolumbar intervertebral disc extrusion and presumptive progressive myelomalacia.非局限性与颅骨局限性广泛半椎板切除术及硬脊膜切开术治疗胸腰椎椎间盘突出并疑似进行性脊髓软化犬的疗效
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本文引用的文献

1
Review: Steroid Use in Patients With Acute Spinal Cord Injury and Guideline Update.综述:急性脊髓损伤患者使用类固醇及指南更新
Korean J Neurotrauma. 2022 Apr 19;18(1):22-30. doi: 10.13004/kjnt.2022.18.e21. eCollection 2022 Apr.
2
Pathophysiology of Spinal Cord Injury.脊髓损伤的病理生理学。
Neurosurg Clin N Am. 2021 Jul;32(3):305-313. doi: 10.1016/j.nec.2021.03.002. Epub 2021 May 7.
3
The safety and efficacy of steroid treatment for acute spinal cord injury: A Systematic Review and meta-analysis.类固醇治疗急性脊髓损伤的安全性和有效性:一项系统评价和荟萃分析。
Heliyon. 2020 Feb 19;6(2):e03414. doi: 10.1016/j.heliyon.2020.e03414. eCollection 2020 Feb.
4
High-dose methylprednisolone for acute traumatic spinal cord injury: A meta-analysis.大剂量甲基强的松龙治疗急性创伤性脊髓损伤:一项荟萃分析。
Neurology. 2019 Aug 27;93(9):e841-e850. doi: 10.1212/WNL.0000000000007998. Epub 2019 Jul 29.
5
Traumatic Spinal Cord Injury Emergency Service Triage Patterns and the Associated Emergency Department Outcomes.创伤性脊髓损伤急救服务分诊模式及相关急诊科结局
J Neurotrauma. 2015 Dec 15;32(24):2008-16. doi: 10.1089/neu.2015.4016. Epub 2015 Sep 9.
6
Epidemiology, demographics, and pathophysiology of acute spinal cord injury.急性脊髓损伤的流行病学、人口统计学及病理生理学
Spine (Phila Pa 1976). 2001 Dec 15;26(24 Suppl):S2-12. doi: 10.1097/00007632-200112151-00002.
7
Therapeutic approaches to spinal cord injury.脊髓损伤的治疗方法。
Adv Neurol. 1997;72:377-86.
8
Evaluation of an intensive methylprednisolone sodium succinate dosing regimen in experimental spinal cord injury.实验性脊髓损伤中甲基强的松龙琥珀酸钠强化给药方案的评估
J Neurosurg. 1987 Jul;67(1):102-5. doi: 10.3171/jns.1987.67.1.0102.
9
A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study.一项关于甲基泼尼松龙或纳洛酮治疗急性脊髓损伤的随机对照试验。第二次全国急性脊髓损伤研究结果。
N Engl J Med. 1990 May 17;322(20):1405-11. doi: 10.1056/NEJM199005173222001.
10
Incidence of traumatic spinal cord lesions.创伤性脊髓损伤的发病率。
J Chronic Dis. 1975 Oct;28(9):471-92. doi: 10.1016/0021-9681(75)90057-0.