Malta Deborah Carvalho, Gomes Crizian Saar, Veloso Guilherme Augusto, Teixeira Renato Azeredo, Felisbino Mendes Mariana Santos, Brant Luisa Campos Caldeira, Prates Elton Junio Sady, Silva Alanna Gomes, Souza Juliana Bottoni de, Duncan Bruce Bartholow, Schmidt Maria Inês, Souza Maria de Fátima Marinho de, Vasconcelos Ana Maria Nogales, Szwarcwald Célia Landmann, Velásquez Meléndez Jorge Gustavo, Machado Ísis Eloah, Naghavi Mohsen, Ribeiro Antônio Luiz Pinho
Universidade Federal de Minas Gerais, Escola de Enfermagem, Belo Horizonte, Minas Gerais, Brazil.
Universidade Federal de Minas Gerais, Faculdade de Medicina, Belo Horizonte, Minas Gerais, Brazil.
Public Health. 2024 Nov;236:422-429. doi: 10.1016/j.puhe.2024.09.006. Epub 2024 Sep 20.
The aim of this study was to analyse the burden of disease due to noncommunicable diseases (NCDs) between 1990 and 2021 in Brazil. In addition, this study compared mortality from NCDs with mortality from all causes and COVID-19, analysed NCD mortality trends and projections for 2030, and analysed NCD mortality rates and risk factors attributed to these deaths among the 27 states of Brazil.
Ecological studies.
This study used the Global Burden of Disease study (GBD) database from 1990 to 2021. Premature deaths from four NCDs (neoplasms, cardiovascular disease, chronic respiratory diseases and diabetes mellitus) were analysed. The following metrics were used to analyse the burden of NCDs in Brazil: absolute number of deaths, proportional mortality, mortality rate, years of life lost due to premature death (YLL), years lived with disabilities (YLD) and disability-adjusted years of life lost due to premature death (DALY). For comparison between the years studied and states, age-standardised rates were used.
Finding from this study showed that there was increase in the proportion of premature deaths due to NCDs between 1990 and 2019 (29.4 % in 1990, 30.8 % in 2019), and a reduction in 2021 (24.7 %). The mortality rates, DALY and YLL from NCDs declined between 1990 and 2019 (-37.7 %, -34.5 % and -38.3 %, respectively); however, a stability in mortality rates, DALY, YLD, YLL was observed between 2019 and 2021 (-0.1 %, 0.7 %, -0.1 % and 0.8 %, respectively). Between 1990 and 2021, there was a decline in mortality rates, DALY and YLL for most states and an increase in YLD rates. However, results suggest that the Sustainable Development Goal (SDG) for the reduction in mortality from NCDs by one-third by 2030 will not be achieved. The main risk factors associated with premature death from NCDs in 2021 were high blood pressure, tobacco use, dietary risks, high body mass index (BMI) and high blood glucose levels. The correlation between sociodemographic index and percentage change in mortality rates was significant for the following total NCDs, cardiovascular disease, chronic respiratory disease, diabetes and neoplasms.
The current study highlights the importance of deaths from NCDs in Brazil and the worsening of mortality rates since 2016, as a result of austerity measures and the COVID-19 pandemic, which compromises the achievement of the SDG reduced mortality targets for NCDs. There was a reduction in risk factors for NCDs, mainly behavioural, although metabolic risk factors are of great concern and require new strategies to promote health, prevention and comprehensive care.
本研究旨在分析1990年至2021年期间巴西非传染性疾病(NCD)造成的疾病负担。此外,本研究比较了非传染性疾病死亡率与全因死亡率及新冠肺炎死亡率,分析了2030年非传染性疾病死亡率趋势和预测,并分析了巴西27个州中这些死亡归因的非传染性疾病死亡率及风险因素。
生态学研究。
本研究使用了1990年至2021年的全球疾病负担研究(GBD)数据库。分析了四种非传染性疾病(肿瘤、心血管疾病、慢性呼吸道疾病和糖尿病)导致的过早死亡。使用以下指标分析巴西非传染性疾病负担:死亡绝对数、比例死亡率、死亡率、过早死亡导致的生命年损失(YLL)、带病生存年数(YLD)以及过早死亡导致的伤残调整生命年损失(DALY)。为了在所研究年份和各州之间进行比较,使用了年龄标准化率。
本研究结果表明,1990年至2019年期间非传染性疾病导致的过早死亡比例有所上升(1990年为29.4%,2019年为30.8%),而2021年有所下降(24.7%)。1990年至2019年期间,非传染性疾病的死亡率、DALY和YLL有所下降(分别下降37.7%、34.5%和38.3%);然而,2019年至2021年期间,死亡率、DALY、YLD、YLL保持稳定(分别为-0.1%、0.7%、-0.1%和0.8%)。1990年至2021年期间,大多数州的死亡率、DALY和YLL有所下降,YLD率有所上升。然而,结果表明,到2030年将非传染性疾病死亡率降低三分之一的可持续发展目标(SDG)无法实现。2021年与非传染性疾病过早死亡相关的主要风险因素是高血压、烟草使用、饮食风险、高体重指数(BMI)和高血糖水平。社会人口学指数与死亡率变化百分比之间的相关性在以下非传染性疾病总数、心血管疾病、慢性呼吸道疾病糖尿病和肿瘤方面具有显著性。
本研究强调了巴西非传染性疾病死亡的重要性以及自2016年以来由于紧缩措施和新冠肺炎疫情导致的死亡率恶化,这损害了实现非传染性疾病死亡率降低的可持续发展目标。非传染性疾病的风险因素有所减少,主要是行为方面的,尽管代谢风险因素令人高度担忧,需要新的战略来促进健康、预防和全面护理。