Department of Pharmacy, "G. D'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Department of Physical and Analytical Chemistry, University of Jaén, Campus Las Lagunillas S/N, E-23071 Jaén, Spain.
Food Chem. 2025 Jan 15;463(Pt 2):141323. doi: 10.1016/j.foodchem.2024.141323. Epub 2024 Sep 18.
The circular economy is gaining attention around the world as a sustainable approach to tackling environmental problems, promoting more responsible management of resources. The aim of this work is the valorization of grape pomace as a waste product of agrifood chain. We prepared decoction (DC), ultrasound-assisted and microwave-assisted extracts (UAE and MAE respectively) of grape pomace, determining their phytochemical profile (using HPLC-ESI-Q-TOF-MS), antioxidant activity and enzyme inhibitory effects. Then, the results were compared with those of raisins and several edible berries already present in the market. Grape pomace extracts presented the highest total phenolic content (62-68 mg gallic acid equivalents/g; mg GAE/g), whereas the concentrations in the other berries were 4-43 mg GAE/g. These results were in agreement with the higher antioxidant activity and tyrosinase inhibition observed in grape pomace compared with the other berries, except for the metal chelating activity. The main compounds in grape pomace extracts were flavonoids (particularly quercetin glycosides), followed by organic acids (citric, isocitric and gallic acids). These results open new perspectives in the development of food supplements and nutraceuticals based on grape pomace extracts.
循环经济作为一种应对环境问题、促进资源更负责任管理的可持续方法，正在全球范围内受到关注。这项工作的目的是对葡萄渣作为农业食品链的废弃物进行增值利用。我们分别制备了葡萄渣的煎煮液（DC）、超声辅助提取液（UAE）和微波辅助提取液（MAE），并测定了它们的植物化学成分谱（使用 HPLC-ESI-Q-TOF-MS）、抗氧化活性和酶抑制作用。然后，将结果与葡萄干和几种已在市场上销售的食用浆果进行了比较。葡萄渣提取物的总酚含量最高（62-68 mg 没食子酸当量/克；mg GAE/g），而其他浆果中的浓度为 4-43 mg GAE/g。这些结果与葡萄渣提取物的抗氧化活性和酪氨酸酶抑制活性高于其他浆果的结果一致，只是金属螯合活性除外。葡萄渣提取物中的主要化合物为类黄酮（特别是槲皮素糖苷），其次为有机酸（柠檬酸、异柠檬酸和没食子酸）。这些结果为基于葡萄渣提取物开发食品补充剂和营养保健品开辟了新的前景。
