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孟加拉国中风的患病率:系统评价和荟萃分析。

Prevalence of stroke in Bangladesh: A systematic review and meta-analysis.

机构信息

Department of Statistics, Noakhali Science and Technology University, Noakhali, Bangladesh.

Department of Statistics, Noakhali Science and Technology University, Noakhali, Bangladesh.

出版信息

J Stroke Cerebrovasc Dis. 2024 Dec;33(12):108017. doi: 10.1016/j.jstrokecerebrovasdis.2024.108017. Epub 2024 Sep 19.

Abstract

BACKGROUND

Stroke is a major health concern in Bangladesh due to its high incidence and effect on rates of morbidity and death. The morbidity due to stroke in Bangladesh is indeed increasing. This study aimed to find the pooled prevalence of stroke in Bangladesh.

METHODS

An extensive search was conducted using PubMed, MEDLINE, and Google Scholar databases. I and Q-tests were employed to evaluate the heterogeneity. A random-effects model and subgroup analysis were performed due to the significant heterogeneity. We used Egger's test and funnel plot to look at publication bias. Meta-regression was carried out to analyze how different study variables influenced the effect estimates and to explore sources of heterogeneity across studies. The GRADE approach was used to evaluate the overall quality of the evidence, and the Joanna Briggs Institute tool was used to assess the risk of bias. Sensitivity analysis was conducted to evaluate the robustness of the meta-analysis results. STATA version 17 was used for analysis.

RESULTS

We selected eleven (n = 1577293) studies that met the inclusion criteria for the final synthesis. In Bangladesh, the overall pooled prevalence of stroke was 1.10 % (95 % CI: 0.70-1.51). Subgroup analysis showed that the prevalence of stroke was 1.14 % (95 % CI: 0.58-1.70) from 2005 to 2014 and 1.04 % (95 % CI: 0.40-1.68) from 2015 to 2024.

CONCLUSION

Stroke prevalence in Bangladesh is significantly high. The country's healthcare system faces adequate stroke prevention and treatment challenges. Improving healthcare services and public health education are crucial to addressing this increasing public health issue.

摘要

背景

由于高发病率以及对发病率和死亡率的影响,中风是孟加拉国的一个主要健康关注点。孟加拉国因中风导致的发病率确实在不断上升。本研究旨在确定孟加拉国中风的综合患病率。

方法

通过使用 PubMed、MEDLINE 和 Google Scholar 数据库进行广泛搜索。采用 I² 和 Q 检验来评估异质性。由于存在显著异质性,因此进行了随机效应模型和亚组分析。我们使用 Egger 检验和漏斗图来观察发表偏倚。进行元回归分析,以了解不同研究变量如何影响效应估计值,并探索研究之间异质性的来源。使用 GRADE 方法评估证据的总体质量,并使用 Joanna Briggs 研究所工具评估偏倚风险。进行敏感性分析以评估荟萃分析结果的稳健性。使用 STATA 版本 17 进行分析。

结果

我们选择了符合最终综合纳入标准的 11 项研究(n=1577293)。在孟加拉国,中风的总体综合患病率为 1.10%(95%CI:0.70-1.51)。亚组分析显示,2005 年至 2014 年期间中风的患病率为 1.14%(95%CI:0.58-1.70),而 2015 年至 2024 年期间为 1.04%(95%CI:0.40-1.68)。

结论

孟加拉国的中风患病率显著较高。该国的医疗保健系统面临着充分的中风预防和治疗挑战。改善医疗服务和公共卫生教育对于应对这一日益严重的公共卫生问题至关重要。

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