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褪黑素对青春期前雌性大鼠分散垂体细胞促黄体生成素刺激释放的差异作用。

Differential effects of melatonin on the stimulated release of LH from dispersed pituitary cells of the prepubertal female rat.

作者信息

Symons A M, Arendt J, Pryde S J

出版信息

J Endocrinol. 1985 Oct;107(1):107-12. doi: 10.1677/joe.0.1070107.

DOI:10.1677/joe.0.1070107
PMID:3930648
Abstract

The effect of melatonin on the stimulated release of LH from prepubertal female rat pituitary cells in vitro was investigated. Significant inhibition of LH-releasing hormone and calcium ionophore-induced LH release was seen but not of potassium-induced release. These results suggest a specific interaction between melatonin and the endogenous events leading to LH release, and may implicate melatonin as an important neuroendocrine component of pubertal development in this species.

摘要

研究了褪黑素对体外培养的青春期前雌性大鼠垂体细胞促黄体生成素（LH）刺激释放的影响。结果发现，褪黑素对促性腺激素释放激素（LH - releasing hormone）和钙离子载体诱导的LH释放有显著抑制作用，但对钾离子诱导的释放没有抑制作用。这些结果表明褪黑素与导致LH释放的内源性事件之间存在特定相互作用，并且可能意味着褪黑素是该物种青春期发育的重要神经内分泌成分。

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Differential effects of melatonin on the stimulated release of LH from dispersed pituitary cells of the prepubertal female rat.褪黑素对青春期前雌性大鼠分散垂体细胞促黄体生成素刺激释放的差异作用。
J Endocrinol. 1985 Oct;107(1):107-12. doi: 10.1677/joe.0.1070107.
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Melatonin inhibition of the neonatal pituitary response to luteinizing hormone-releasing factor.褪黑素对新生儿垂体对促黄体生成素释放因子反应的抑制作用。
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Inhibition of the in vitro pituitary response to luteinizing hormone-releasing hormone by melatonin, serotonin, and 5-methoxytryptamine.褪黑素、血清素和5-甲氧基色胺对垂体体外对促黄体生成素释放激素反应的抑制作用。
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Sex differences in pituitary LH storage and release in LHRH-stimulated pubertal rats. A correlative immunohistochemical and radioimmunoassay study.促黄体生成素释放激素刺激的青春期大鼠垂体促黄体生成素储存和释放的性别差异。一项相关免疫组织化学和放射免疫分析研究。
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