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2007 - 2022年前列腺癌检测活检前MRI使用趋势

Trends in pre-biopsy MRI usage for prostate cancer detection, 2007-2022.

作者信息

Soerensen Simon John Christoph, Li Shufeng, Langston Marvin E, Fan Richard E, Rusu Mirabela, Sonn Geoffrey A

机构信息

Department of Urology, Stanford University School of Medicine, Stanford, CA, USA.

Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA.

出版信息

Prostate Cancer Prostatic Dis. 2025 Jun;28(2):519-522. doi: 10.1038/s41391-024-00896-y. Epub 2024 Sep 21.

Abstract

BACKGROUND

Clinical guidelines favor MRI before prostate biopsy due to proven benefits. However, adoption patterns across the US are unclear.

METHODS

This study used the Merative™ Marketscan® Commercial & Medicare Databases to analyze 872,829 prostate biopsies in 726,663 men from 2007-2022. Pre-biopsy pelvic MRI within 90 days was the primary outcome. Descriptive statistics and generalized estimating equations assessed changes over time, urban-rural differences, and state-level variation.

RESULTS

Pre-biopsy MRI utilization increased significantly from 0.5% in 2007 to 35.5% in 2022, with faster adoption in urban areas (36.1% in 2022) versus rural areas (28.3% in 2022). Geographic disparities were notable, with higher utilization in California, New York, and Minnesota, and lower rates in the Southeast and Mountain West.

CONCLUSIONS

The study reveals a paradigm shift in prostate cancer diagnostics towards MRI-guided approaches, influenced by evolving guidelines and clinical evidence. Disparities in access, particularly in rural areas and specific regions, highlight the need for targeted interventions to ensure equitable access to advanced diagnostic techniques.

摘要

背景

由于已证实的益处,临床指南倾向于在前列腺活检前进行磁共振成像(MRI)检查。然而,美国各地的采用模式尚不清楚。

方法

本研究使用了美励®市场扫描®商业与医疗保险数据库,分析了2007年至2022年期间726,663名男性中的872,829次前列腺活检。主要观察指标是活检前90天内的盆腔MRI检查。描述性统计和广义估计方程评估了随时间的变化、城乡差异以及州级差异。

结果

活检前MRI的使用率从2007年的0.5%显著增加到2022年的35.5%,城市地区(2022年为36.1%)的采用速度快于农村地区(2022年为28.3%)。地理差异显著,加利福尼亚州、纽约州和明尼苏达州的使用率较高,而东南部和西部山区的使用率较低。

结论

该研究揭示了前列腺癌诊断向MRI引导方法的范式转变,这受到不断发展的指南和临床证据的影响。在获取方面的差异,特别是在农村地区和特定区域,凸显了需要有针对性的干预措施,以确保公平获得先进的诊断技术。

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