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人类下颌下唾液腺阻塞性腺炎的组织化学研究。I. 乳铁蛋白、溶菌酶和癌胚抗原的免疫组织化学显示

Histochemical studies of obstructive adenitis in human submandibular salivary glands. I. Immunohistochemical demonstration of lactoferrin, lysozyme and carcinoembryonic antigen.

作者信息

Tsukitani K, Nakai M, Tatemoto Y, Hikosaka N, Mori M

出版信息

J Oral Pathol. 1985 Sep;14(8):631-8. doi: 10.1111/j.1600-0714.1985.tb00540.x.

DOI:10.1111/j.1600-0714.1985.tb00540.x
PMID:3930673
Abstract

Immunohistochemical detection of lactoferrin (LF), lysozyme (LZ) and carcinoembryonic antigen (CEA) was made in obstructive adenitis of the submandibular glands. Atrophic and altered acinar cells in the early stage of the lesion stained strongly for LF, whereas they were unreactive or stained slightly for LZ. Ductal cells usually stained for LZ. Staining for CEA was strong and irregularly distributed in altered acinar cells. Duct-like structures and dilated ductal segments in the chronic stage were generally negative for LF, LZ and CEA. Secretory components in luminal cavities gave abundant staining for LF, LZ and CEA. Histocytes which infiltrated into the connective tissue in the later stage showed a positive LZ reaction.

摘要

对颌下腺阻塞性腺炎进行乳铁蛋白(LF)、溶菌酶(LZ)和癌胚抗原(CEA)的免疫组织化学检测。病变早期萎缩和改变的腺泡细胞LF染色强,而LZ染色无反应或轻度染色。导管细胞通常为LZ染色阳性。CEA染色在改变的腺泡细胞中呈强阳性且分布不规则。慢性期的导管样结构和扩张的导管段通常对LF、LZ和CEA呈阴性。管腔内的分泌成分对LF、LZ和CEA染色丰富。后期浸润到结缔组织中的组织细胞LZ反应呈阳性。

相似文献

1
Histochemical studies of obstructive adenitis in human submandibular salivary glands. I. Immunohistochemical demonstration of lactoferrin, lysozyme and carcinoembryonic antigen.人类下颌下唾液腺阻塞性腺炎的组织化学研究。I. 乳铁蛋白、溶菌酶和癌胚抗原的免疫组织化学显示
J Oral Pathol. 1985 Sep;14(8):631-8. doi: 10.1111/j.1600-0714.1985.tb00540.x.
2
Histochemical studies of obstructive adenitis in human submandibular salivary glands. II. Lectin binding and keratin distribution in the lesions.人类下颌下唾液腺阻塞性腺炎的组织化学研究。II. 病变中的凝集素结合和角蛋白分布
J Oral Pathol. 1985 Oct;14(9):671-9. doi: 10.1111/j.1600-0714.1985.tb00546.x.
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Immunohistochemical observations on carbonic anhydrase I and II in human salivary glands and submandibular obstructive adenitis.人唾液腺及下颌下阻塞性腺炎中碳酸酐酶I和II的免疫组织化学观察
J Oral Pathol. 1986 Apr;15(4):187-90. doi: 10.1111/j.1600-0714.1986.tb00604.x.
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Characterization of cells in salivary gland lesions by immunohistochemical identification of carcinoembryonic antigens.通过癌胚抗原的免疫组织化学鉴定对唾液腺病变中的细胞进行特征描述。
Oral Surg Oral Med Oral Pathol. 1985 Jun;59(6):595-9. doi: 10.1016/0030-4220(85)90188-4.
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[Immunopathologic reactions in chronic sialadenitis of the submandibular gland (so-called Küttner tumor)].[下颌下腺慢性涎腺炎(所谓的库特纳瘤)中的免疫病理反应]
Laryngol Rhinol Otol (Stuttg). 1984 Sep;63(9):468-74.
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[Immunohistochemical localization of lactoferrin, lysozyme and secretory component in inflamed salivary gland tissues].
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J Oral Pathol Med. 1992 Sep;21(8):370-5. doi: 10.1111/j.1600-0714.1992.tb01368.x.

引用本文的文献

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Immunohistochemical localization of alpha 1-antitrypsin and alpha 1-antichymotrypsin in salivary pleomorphic adenomas.α1-抗胰蛋白酶和α1-抗糜蛋白酶在涎腺多形性腺瘤中的免疫组织化学定位
Virchows Arch A Pathol Anat Histopathol. 1985;408(2-3):107-16. doi: 10.1007/BF00707975.
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Multiple expression of tissue markers in mucoepidermoid carcinomas and acinic cell carcinomas of the salivary glands.涎腺黏液表皮样癌和腺泡细胞癌中组织标志物的多重表达。
Virchows Arch A Pathol Anat Histopathol. 1989;414(5):407-13. doi: 10.1007/BF00718624.
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Immunohistochemical characterization of epithelial cells in human lacrimal glands. II. Inflammatory and neoplastic lesions of lacrimal glands.
人泪腺上皮细胞的免疫组织化学特征。II. 泪腺的炎性和肿瘤性病变。
Graefes Arch Clin Exp Ophthalmol. 1990;228(1):65-72. doi: 10.1007/BF02764294.