Boonnijasin Ongon, Kanchanapoomi Kantima, Srisuwatchari Witchaya, Pacharn Punchama, Visitsunthorn Nualanong, Jirapongsananuruk Orathai
Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Asian Pac J Allergy Immunol. 2024 Sep 22. doi: 10.12932/AP-030124-1757.
Visual analog scale (VAS) correlates well with total nasal symptom score (TNSS) but negatively correlates with peak nasal inspiratory flow (PNIF) in adults with allergic rhinitis (AR). Small children may not rate VAS properly and parents usually help assess their child's symptoms. Data on the correlations among parent-assessed VAS (P-VAS), VAS, TNSS, and PNIF in children with AR was limited.
To assess correlations among P-VAS, VAS, TNSS, and PNIF in children and adolescents with perennial AR (PAR).
Patients with PAR aged 6-18 years and their parents were instructed to record daily VAS, TNSS, PNIF, and P-VAS in an electronic diary for 8 weeks.
2387 records from 46 patients (56.5% male) were obtained. VAS and P-VAS showed a strong correlation (rs = 0.82, p < 0.001). Moderate correlations were found between VAS vs TNSS (rs = 0.53, p < 0.001) and between P-VAS vs TNSS (rs = 0.48, p < 0.001). There was a weak negative correlation between PNIF vs VAS, PNIF vs TNSS, and PNIF vs P-VAS (rs = -0.20, rs = -0.22, rs = -0.18, p < 0.001 respectively). In addition, a weak negative correlation was found between nasal congestion and PNIF (rs = -0.26, p < 0.001). The overall inter-rater agreement between VAS and TNSS was fair (Kappa = 0.37, p < 0.001). Higher inter-rater agreement was found in moderate-severe than in the mild PAR group (Kappa = 0.50 vs 0.17) and in adolescents than in the children group (Kappa = 0.44 vs 0.26).
In small children, P-VAS was a reliable tool to assess nasal symptoms. Both subjective and objective measurements provided complementary information for symptom monitoring in patients with AR.
视觉模拟评分法（VAS）与变应性鼻炎（AR）成年患者的总鼻症状评分（TNSS）具有良好的相关性，但与鼻吸气峰流量（PNIF）呈负相关。幼儿可能无法正确进行VAS评分，通常由家长协助评估孩子的症状。关于AR患儿家长评估的VAS（P-VAS）、VAS、TNSS和PNIF之间相关性的数据有限。
评估常年性AR（PAR）儿童和青少年中P-VAS、VAS、TNSS和PNIF之间的相关性。
年龄在6至18岁的PAR患者及其家长被要求在电子日记中记录8周的每日VAS、TNSS、PNIF和P-VAS。
获得了46例患者（男性占56.5%）的2387条记录。VAS和P-VAS显示出强相关性（rs = 0.82，p < 0.001）。VAS与TNSS之间（rs = 0.53，p < 0.001）以及P-VAS与TNSS之间（rs = 0.48，p < 0.001）发现有中度相关性。PNIF与VAS、PNIF与TNSS以及PNIF与P-VAS之间存在弱负相关性（分别为rs = -0.20，rs = -0.22，rs = -0.18，p < 0.001）。此外，鼻充血与PNIF之间发现有弱负相关性（rs = -0.26，p < 0.001）。VAS和TNSS之间的总体评分者间一致性为中等（Kappa = 0.37，p < 0.001）。中重度PAR组的评分者间一致性高于轻度组（Kappa = 0.50对0.17），青少年组高于儿童组（Kappa = 0.44对0.26）。
在幼儿中，P-VAS是评估鼻症状的可靠工具。主观和客观测量均为AR患者的症状监测提供了补充信息。
