Puntis J W, Candy D C, Alexander-Williams J, Kelsey A
J Pediatr Gastroenterol Nutr. 1985 Oct;4(5):826-8. doi: 10.1097/00005176-198510000-00025.
Cutaneous lesions containing Crohn's granulomata are rare and tend to occur in submammary or abdominal wall skin folds when they are to be found (1). Crohn's disease of the skin in nonflexural locations has been reported (2,3) although not in children. We report a 5-year-old girl with extensive colonic Crohn's disease, who at presentation was noted to have a generalised erythematous papular rash which histologically showed typical noncaseating granulomata.
含有克罗恩肉芽肿的皮肤病变很少见,一旦出现,往往发生在乳房下或腹壁皮肤褶皱处(1)。已有报道非褶皱部位的皮肤克罗恩病(2,3),但未见于儿童。我们报告一名患有广泛性结肠克罗恩病的5岁女孩,就诊时发现有全身性红斑丘疹皮疹,组织学检查显示为典型的非干酪样肉芽肿。