Calder C J, Lacy D, Raafat F, Weller P H, Booth I W
Department of Pathology, Children's Hospital, Birmingham.
Gut. 1993 Nov;34(11):1636-8. doi: 10.1136/gut.34.11.1636.
Extra-intestinal or metastatic Crohn's disease is being recognised increasingly, most commonly in the skin and genitourinary system. Only very rarely has it been reported in the lung. A 3 year old boy who presented with swollen gums and a persistent abnormality on his chest x ray is reported. Lung biopsy specimens showed multiple non-caseating epithelioid granulomas. Subsequent investigation showed the presence of intestinal Crohn's disease. The evidence for abnormal lung function in Crohn's disease and the possible pathogenesis of metastatic pulmonary Crohn's disease are discussed.
肠外或转移性克罗恩病越来越受到关注，最常见于皮肤和泌尿生殖系统。在肺部的报道极为罕见。本文报道了一名3岁男孩，他出现牙龈肿胀且胸部X线持续异常。肺活检标本显示多个非干酪样上皮样肉芽肿。后续检查发现存在肠道克罗恩病。本文还讨论了克罗恩病肺功能异常的证据以及转移性肺克罗恩病的可能发病机制。
