Macrynikola Natalia, Chang Sarah, Torous John
Division of Digital Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Can J Psychiatry. 2024 Sep 23:7067437241274201. doi: 10.1177/07067437241274201.
Digital mental health interventions have shown promise for alleviating various forms of psychopathology, including depression and anxiety. However, the mechanisms of such interventions remain largely unexplored. The purpose of this study was to investigate a potential mechanistic process through which one hybrid digital mental health intervention (i.e., the Digital Clinic) might operate. We hypothesized that emotion regulation (ER) self-efficacy at the treatment midpoint may mediate the relationship between alliance (i.e., therapeutic alliance and digital alliance) and outcome (i.e., co-morbid symptoms of depression and anxiety) at the treatment endpoint.
Data used in this study came from the Digital Clinic, a brief transdiagnostic telehealth treatment program augmented by a dual-purpose digital phenotyping and intervention smartphone app. Recruited primarily from primary care, participants were 82 adults (73% White, 64% cisgender women, mean age 41) receiving outpatient treatment in the northeastern United States. All constructs were measured with validated scales, including The Working Alliance Inventory-Short Revised (WAI-SR) for therapeutic alliance, the Digital Working Alliance Inventory (DWAI) for digital alliance, the PROMIS Self-Efficacy for Managing Emotions Short Form scale for ER self-efficacy, and the Patient Health Questionnaire Anxiety-Depression Scale (PHQ-ADS) for co-morbid symptoms of depression and anxiety.
Significant reductions in co-morbid symptoms of depression and anxiety and significant increases in ER self-efficacy were found from baseline to treatment endpoint. Therapeutic and digital alliance at the midpoint each predicted reductions in co-morbid symptoms of depression and anxiety at the endpoint through ER self-efficacy, controlling for baseline scores.
Findings suggest that ER self-efficacy may be a proximal predictor of clinical improvement that may be enhanced by therapeutic and digital alliance. Future controlled research is essential to improve knowledge of the mechanisms of digital mental health interventions and to enhance their effectiveness.
数字心理健康干预已显示出缓解包括抑郁和焦虑在内的各种精神病理学形式的前景。然而,此类干预的机制在很大程度上仍未得到探索。本研究的目的是调查一种混合数字心理健康干预措施(即数字诊所)可能发挥作用的潜在机制过程。我们假设治疗中点时的情绪调节(ER)自我效能感可能会在治疗终点时调节联盟(即治疗联盟和数字联盟)与结果(即抑郁和焦虑的共病症状)之间的关系。
本研究中使用的数据来自数字诊所,这是一个简短的跨诊断远程医疗治疗项目,通过一个具有双重用途的数字表型分析和干预智能手机应用程序得到增强。主要从初级保健机构招募参与者,82名成年人(73%为白人,64%为顺性别女性,平均年龄41岁)在美国东北部接受门诊治疗。所有构念均使用经过验证的量表进行测量,包括用于治疗联盟的《工作联盟量表 - 简短修订版》(WAI - SR)、用于数字联盟的《数字工作联盟量表》(DWAI)、用于ER自我效能感的《PROMIS情绪管理自我效能感简表》以及用于抑郁和焦虑共病症状的《患者健康问卷焦虑 - 抑郁量表》(PHQ - ADS)。
从基线到治疗终点,抑郁和焦虑的共病症状显著减少,ER自我效能感显著增加。在控制基线分数的情况下,中点时的治疗联盟和数字联盟各自通过ER自我效能感预测了终点时抑郁和焦虑共病症状的减少。
研究结果表明,ER自我效能感可能是临床改善的近端预测因素,治疗联盟和数字联盟可能会增强这一因素。未来的对照研究对于提高对数字心理健康干预机制的认识并增强其有效性至关重要。