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采用伴随基质诱导自体软骨细胞植入、髌股内侧韧带重建和胫骨结节截骨术治疗髌骨软骨损伤。

Treatment of Patellar Chondral Lesions With Concomitant Matrix-Induced Autologous Chondrocyte Implantation, Medial Patellofemoral Ligament Reconstruction, and Tibial Tubercle Osteotomy.

作者信息

Fletcher Connor, Rizy Morgan, Gomoll Andreas, Strickland Sabrina

机构信息

Division of Sports Medicine, Hospital for Special Surgery, New York, New York, U.S.A.

出版信息

Arthrosc Tech. 2024 Jun 5;13(9):103059. doi: 10.1016/j.eats.2024.103059. eCollection 2024 Sep.

Abstract

The US Food and Drug Administration approved matrix-induced autologous chondrocyte implantation (MACI) for use in the United States in 2016, and it has proven to be an effective treatment for articular cartilage defects in the knee. Concomitant patellar stabilization and realignment procedures, such as tibial tubercle osteotomy (TTO) and medial patellofemoral ligament (MPFL) reconstruction, are often performed with MACI to prevent further damage to the knee and to sustain the integrity of the cartilage repair. This Technical Note aims to describe MACI in the patella with concomitant patellar stabilization and realignment and to provide a treatment algorithm for when various simultaneous procedures are indicated. The authors believe that correction of patellar malalignment and instability is crucial to the success of cartilage repair procedures. Therefore, we recommend that TTO and MPFL reconstruction be performed with MACI procedures of the patella when the anatomic pathology and pertinent patient history, such as articular cartilage defects with patellar instability and abnormal patellar alignment, are present.

摘要

美国食品药品监督管理局于2016年批准基质诱导自体软骨细胞植入术(MACI)在美国使用,事实证明它是治疗膝关节软骨缺损的有效方法。通常会同时进行髌骨稳定和复位手术,如胫骨结节截骨术(TTO)和内侧髌股韧带(MPFL)重建术,与MACI一起进行,以防止对膝关节造成进一步损伤,并维持软骨修复的完整性。本技术说明旨在描述伴有髌骨稳定和复位的髌骨MACI,并提供在需要进行各种同步手术时的治疗算法。作者认为,纠正髌骨排列不齐和不稳定对软骨修复手术的成功至关重要。因此,我们建议,当存在解剖病理学和相关患者病史,如伴有髌骨不稳定和髌骨排列异常的关节软骨缺损时,在髌骨MACI手术中同时进行TTO和MPFL重建术。

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