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探索糖尿病与慢性肺病之间的相互关系:一项综合综述。

Exploring the Interrelationship Between Diabetes Mellitus and Chronic Lung Diseases: A Comprehensive Review.

作者信息

Tarar Pakeeza, Bandi Venkata Varshitha, Sarwar Hooria, Maged Rafik, Sinha Mohit, Koneru Hema Manvi, Malasevskaia Iana

机构信息

Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Medical Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

出版信息

Cureus. 2024 Sep 17;16(9):e69617. doi: 10.7759/cureus.69617. eCollection 2024 Sep.

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder that affects millions of individuals worldwide. With an increasing prevalence, understanding its implications for respiratory health is essential. Chronic lung diseases, such as asthma and chronic obstructive pulmonary disease (COPD), significantly impact morbidity and healthcare costs, with COPD alone accounting for substantial economic burdens. This comprehensive review investigates the intricate relationship between DM and chronic lung diseases. A systematic search across multiple databases yielded 1,078 articles, from which 10 studies were selected for detailed examination. The findings reveal a bidirectional relationship: diabetes increases the risk of developing chronic lung conditions, while chronic lung diseases can exacerbate glycemic control. Shared inflammatory pathways and comorbidities complicate patient outcomes, underscoring the urgent need for integrated treatment approaches. By elucidating the mechanisms linking these conditions, this review provides valuable insights for healthcare professionals, emphasizing the importance of interdisciplinary care to enhance the quality of life for individuals affected by both diabetes and chronic lung diseases. The results highlight the necessity for further research to explore targeted therapies and preventive measures addressing these interconnected health issues.

摘要

糖尿病(DM)是一种慢性代谢紊乱疾病,影响着全球数百万人。随着患病率的不断上升,了解其对呼吸健康的影响至关重要。慢性肺部疾病,如哮喘和慢性阻塞性肺疾病(COPD),会显著影响发病率和医疗成本,仅COPD就造成了巨大的经济负担。这篇综述全面研究了糖尿病与慢性肺部疾病之间的复杂关系。通过对多个数据库进行系统检索,共获得1078篇文章,从中选取了10项研究进行详细审查。研究结果揭示了一种双向关系:糖尿病会增加患慢性肺部疾病的风险,而慢性肺部疾病会使血糖控制恶化。共同的炎症途径和合并症使患者的病情复杂化,凸显了采用综合治疗方法的迫切需求。通过阐明这些疾病之间的联系机制,本综述为医疗保健专业人员提供了有价值的见解,强调了跨学科护理对于提高糖尿病和慢性肺部疾病患者生活质量的重要性。研究结果强调了进一步开展研究以探索针对这些相互关联的健康问题的靶向治疗和预防措施的必要性。

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