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一名多发性硬化症患者发生皮肤感染。 (你提供的原文“Cutaneous infection with in a patient with multiple sclerosis.”似乎不完整,“with”后面缺少具体内容)

Cutaneous infection with in a patient with multiple sclerosis.

作者信息

Masoumi Morteza, Sakhaee Fatemeh, Ghazanfari Jajin Morteza, Siadat Seyed Davar, Fateh Abolfazl

机构信息

Department of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.

Microbiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran.

出版信息

IDCases. 2024 Sep 8;38:e02077. doi: 10.1016/j.idcr.2024.e02077. eCollection 2024.

DOI:10.1016/j.idcr.2024.e02077
PMID:39309036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11415944/
Abstract

Cutaneous infections caused by Mycobacterium chelonae can present with a variety of clinical symptoms, depending on the patient's immune status. Here, we report a case involving a 46-year-old woman with multiple sclerosis who developed a cutaneous infection caused by M. chelonae. The initial presentation included skin discoloration on her right wrist, which progressed to a granuloma. Following surgical intervention, the infection led to tissue atrophy and the formation of a deep cavity at the site. Upon identification of the causative pathogen, a treatment regimen consisting of clarithromycin and moxifloxacin was initiated and continued for seven months. The patient showed signs of recovery, with the swelling and deep cavity resolving; however, some redness at the site persists. The patient remains under treatment.

摘要

由龟分枝杆菌引起的皮肤感染可呈现多种临床症状,这取决于患者的免疫状态。在此,我们报告一例涉及一名46岁患有多发性硬化症的女性,她发生了由龟分枝杆菌引起的皮肤感染。最初的表现包括右手腕皮肤变色,随后发展为肉芽肿。手术干预后,感染导致组织萎缩并在该部位形成一个深腔。在确定病原体后,开始使用克拉霉素和莫西沙星组成的治疗方案,并持续了七个月。患者显示出恢复迹象,肿胀和深腔消退;然而,该部位仍有一些发红。患者仍在接受治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eaa/11415944/cd70bc8043e2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eaa/11415944/cd70bc8043e2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eaa/11415944/cd70bc8043e2/gr1.jpg

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JAAD Case Rep. 2021 Nov 16;19:54-57. doi: 10.1016/j.jdcr.2021.11.001. eCollection 2022 Jan.
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Latent tuberculosis infection reactivation in patients with multiple sclerosis in use of disease-modifying therapies: A systematic review.
多发性硬化症患者在使用疾病修正治疗药物时潜伏性结核感染再激活:系统评价。
Mult Scler Relat Disord. 2021 Oct;55:103184. doi: 10.1016/j.msard.2021.103184. Epub 2021 Aug 1.
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cutaneous infection: An opportunistic disease in an immunosuppressed patient with myasthenia gravis.皮肤感染:重症肌无力免疫抑制患者的一种机会性疾病。
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