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Leigh has no Brakes: Impaired Inhibition in a Mouse Model of Leigh Syndrome Leads to Enhanced Seizure Sensitivity.Leigh综合征无制动机制：Leigh综合征小鼠模型中抑制功能受损导致癫痫易感性增强。
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本文引用的文献

1
Focusing on mitochondria in the brain: from biology to therapeutics.关注大脑中的线粒体：从生物学到治疗学。
Transl Neurodegener. 2024 Apr 17;13(1):23. doi: 10.1186/s40035-024-00409-w.
2
Drug resistant epilepsy and ketogenic diet: A narrative review of mechanisms of action.耐药性癫痫与生酮饮食：作用机制的叙述性综述
World Neurosurg X. 2024 Feb 25;22:100328. doi: 10.1016/j.wnsx.2024.100328. eCollection 2024 Apr.
3
Mitochondrial dysfunction and neurological disorders: A narrative review and treatment overview.线粒体功能障碍与神经疾病：综述与治疗概述
Life Sci. 2023 Dec 1;334:122257. doi: 10.1016/j.lfs.2023.122257. Epub 2023 Nov 8.
4
Elevated susceptibility to exogenous seizure triggers and impaired interneuron excitability in a mouse model of Leigh syndrome epilepsy. Leigh 综合征癫痫小鼠模型对外源癫痫触发的敏感性升高和中间神经元兴奋性受损。
Neurobiol Dis. 2023 Oct 15;187:106288. doi: 10.1016/j.nbd.2023.106288. Epub 2023 Sep 11.
5
Sudden unexpected death in epilepsy.癫痫相关性猝死
Curr Opin Neurol. 2023 Apr 1;36(2):102-109. doi: 10.1097/WCO.0000000000001135. Epub 2023 Feb 7.
6
Defined neuronal populations drive fatal phenotype in a mouse model of Leigh syndrome.特定神经元群体驱动 Leigh 综合征小鼠模型中的致死表型。
Elife. 2019 Aug 12;8:e47163. doi: 10.7554/eLife.47163.
7
Treatment Outcomes in Patients With Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs: A 30-Year Longitudinal Cohort Study.新诊断癫痫患者使用现有和新型抗癫痫药物治疗的治疗结局：一项长达 30 年的纵向队列研究。
JAMA Neurol. 2018 Mar 1;75(3):279-286. doi: 10.1001/jamaneurol.2017.3949.
8
Cause of Death in Children With Mitochondrial Diseases.线粒体疾病患儿的死因
Pediatr Neurol. 2017 Jan;66:82-88. doi: 10.1016/j.pediatrneurol.2016.10.006. Epub 2016 Oct 13.
9
Ndufs4 related Leigh syndrome: A case report and review of the literature.与Ndufs4相关的 Leigh 综合征：一例病例报告及文献综述
Mitochondrion. 2016 May;28:73-8. doi: 10.1016/j.mito.2016.04.001. Epub 2016 Apr 11.
10
Exercise-induced seizures and lateral asymmetry in patients with temporal lobe epilepsy.颞叶癫痫患者的运动诱发性癫痫发作与侧方不对称性
Epilepsy Behav Case Rep. 2014 Feb 1;2:26-30. doi: 10.1016/j.ebcr.2013.12.004. eCollection 2014.

Leigh has no Brakes: Impaired Inhibition in a Mouse Model of Leigh Syndrome Leads to Enhanced Seizure Sensitivity.

作者信息

Buchanan Gordon F

机构信息

Neurology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, USA.

出版信息

Epilepsy Curr. 2024 Jun 12;24(4):298-300. doi: 10.1177/15357597241257031. eCollection 2024 Jul-Aug.

DOI:10.1177/15357597241257031
PMID:39309059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11412401/
Abstract
摘要