Taqiuddin Rafae, Ali Mohammed Jaffer, Kimmatkar Aishwarya, Lohana Nimerta, Siddiqui Maarya Mohammed, El Rashid Mohamed Yasir Adil, Musaab Ibrahim Mohamed Mohamed Elfatih, Minhaj Rida, Mateen Mohammed Abdul
Shadan Institute of Medical Sciences, Teaching hospital and Research Centre, Hyderabad, India.
Bhaskar Medical college and Bhaskar General Hospital, Hyderabad, India.
Bioinformation. 2024 Jul 31;20(7):719-722. doi: 10.6026/973206300200719. eCollection 2024.
Smoking has emerged as a predominant risk factor for coronary artery disease (CAD) in India, contributing significantly to the country's rising cardiovascular morbidity and mortality rates. The adverse effects of tobacco on cardiovascular health are well-documented, exacerbating a public health challenge in a nation with a high prevalence of smoking. Therefore, it is of interest to analyse the impact of smoking on the incidence and progression of coronary artery disease among the Indian population, emphasizing the need for targeted public health interventions to mitigate this risk factor. We included 1000 adults were enrolled from January to July 2023. The group comprised 500 CAD patients (cases) and 500 individuals without CAD (controls). We gathered information on demographics, smoking habits & other CAD risk factors. To assess the relationships between smoking, CAD, and other variables, we utilized multivariate logistic regression. The analysis revealed that current smokers had a substantially increased likelihood of CAD, with an unadjusted odds ratio (OR) of 3.20 (95% CI: 2.45-4.18), compared to non-smokers. This association remained significant even after adjusting for confounders, with an adjusted OR of 2.80 (95% CI: 2.10-3.75). The study confirms smoking as a critical, Adaptable risk element for CAD, independently increasing the risk of the disease. Smoking significantly elevates the risk of developing coronary artery disease among Indians. Comprehensive anti-smoking campaigns and stringent tobacco control policies are imperative to reduce the burden of CAD. Public health strategies must focus on awareness, prevention, and cessation support to combat this major health threat effectively.
在印度，吸烟已成为冠状动脉疾病（CAD）的主要风险因素，对该国心血管疾病发病率和死亡率的上升起到了显著推动作用。烟草对心血管健康的不利影响已有充分记录，这加剧了一个吸烟率高的国家所面临的公共卫生挑战。因此，分析吸烟对印度人群冠状动脉疾病发病率和进展的影响具有重要意义，强调了针对性公共卫生干预措施以减轻这一风险因素的必要性。我们纳入了2023年1月至7月招募的1000名成年人。该组包括500名CAD患者（病例）和500名无CAD的个体（对照）。我们收集了人口统计学、吸烟习惯及其他CAD风险因素的信息。为评估吸烟、CAD及其他变量之间的关系，我们采用了多因素逻辑回归分析。分析显示，与不吸烟者相比，当前吸烟者患CAD的可能性大幅增加，未调整的优势比（OR）为3.20（95%置信区间：2.45 - 4.18）。即使在对混杂因素进行调整后，这种关联仍然显著，调整后的OR为2.80（95%置信区间：2.10 - 3.75）。该研究证实吸烟是CAD的一个关键、可调整的风险因素，独立增加了患该病的风险。吸烟显著增加了印度人患冠状动脉疾病的风险。全面的反吸烟运动和严格的烟草控制政策对于减轻CAD负担至关重要。公共卫生策略必须注重提高认识、预防和戒烟支持，以有效应对这一重大健康威胁。
