Kappelhoff Jan, Greve Burkhard, Jüstel Thomas
Department of Chemical Engineering, Münster University of Applied Sciences Stegerwaldstraße 39 D-48565 Steinfurt Germany
Department of Radiotherapy - Radiooncology, University Hospital Münster Albert-Schweitzer-Campus 1 D-48149 Münster Germany
RSC Adv. 2024 Sep 20;14(41):29992-29998. doi: 10.1039/d4ra01190b. eCollection 2024 Sep 18.
This work concerns a synthesis method for efficiently luminescent LuPO:Eu nanoscale particles (∼100 nm) as well as their temperature (77-500 K) and time dependent photoluminescence. In addition, the incubation of these particles into cells of a human lung adenocarcinomic cell line A549 is briefly presented. This points to the application for bioimaging and detection of cancer cells in the field of medical diagnostics. The emission spectra of Eu doped LuPO nanoparticles show four [Xe]4f → [Xe]4f transition multiplets between 580 and 720 nm, which are typically for Eu comprising luminescent materials, however the most intense one is the D → F (696.40 nm, 1.78 eV) transition due to the crystallographic position point symmetry of Eu in xenotime LuPO. Such an Eu spectrum is rather useful for diagnostics due to the high penetration depth of 700 nm radiation into tissue.
这项工作涉及一种高效发光的LuPO:Eu纳米级颗粒（约100纳米）的合成方法，以及它们在77 - 500 K温度范围内和随时间变化的光致发光特性。此外，还简要介绍了将这些颗粒孵育到人肺腺癌细胞系A549细胞中的情况。这表明了其在医学诊断领域用于生物成像和癌细胞检测的应用前景。Eu掺杂的LuPO纳米颗粒的发射光谱在580至720纳米之间显示出四个[Xe]4f→[Xe]4f跃迁多重峰，这是含Eu发光材料的典型特征，然而，由于磷钇矿型LuPO中Eu的晶体学点对称，最强的一个是D→F（696.40纳米，1.78电子伏特）跃迁。由于700纳米辐射对组织的高穿透深度，这样的Eu光谱对于诊断相当有用。
