Richards Kristin, Mantri Sneha, Brown Carolyn M, Johnsrud Michael, Arcona Steve, Sasané Rahul
TxCORE, College of Pharmacy, The University of Texas at Austin, Austin, Texas, USA.
Department of Neurology, Duke University, Durham, North Carolina, USA.
Patient Prefer Adherence. 2024 Sep 18;18:1919-1928. doi: 10.2147/PPA.S473991. eCollection 2024.
Medication is an important component of the management of Parkinson's disease (PD), yet few studies investigate factors that inform medication decision-making from the perspective of those who use these therapies. This qualitative study aimed to better understand the medication experiences and perspectives of people with PD (PwPD).
Thirty-two PwPD recruited from five large movement disorder clinics from five US states participated in 1-hour on-line focus groups in 2022. Thematic analysis was used to analyze the data.
Four primary themes (subthemes in parentheses) emerged concerning PD medications: (1) medication effectiveness (uncertainty, inconsistent effects, adjusting expectations); (2) medication burden (morning doses, timing challenges, constant reminder); (3) side effects (toleration, treatment, confusion with disease symptoms); and (4) preferences/requests (important attributes, therapy advancement).
This study identified four core dimensions associated with PD medications from the perspective of PwPD. Results indicate the need for enhanced communication between providers and patients regarding PD medication to reduce the uncertainties and burden associated with PD medication regimens and promote better health outcomes for PwPD.
药物治疗是帕金森病（PD）管理的重要组成部分，但很少有研究从使用这些疗法的患者角度调查影响药物决策的因素。这项定性研究旨在更好地了解帕金森病患者（PwPD）的用药经历和观点。
从美国五个州的五个大型运动障碍诊所招募了32名帕金森病患者，于2022年参加了1小时的在线焦点小组讨论。采用主题分析法对数据进行分析。
出现了四个关于帕金森病药物的主要主题（括号内为子主题）：（1）药物疗效（不确定性、效果不一致、调整期望）；（2）药物负担（晨起剂量、时间安排挑战、持续提醒）；（3）副作用（耐受、治疗、与疾病症状混淆）；以及（4）偏好/需求（重要属性、治疗进展）。
本研究从帕金森病患者的角度确定了与帕金森病药物相关的四个核心维度。结果表明，需要加强医护人员与患者之间关于帕金森病药物的沟通，以减少与帕金森病药物治疗方案相关的不确定性和负担，并为帕金森病患者促进更好的健康结果。
