Kräenbring Mena-Alexander, Özcan Fatih, Segets Doris
Institute for Energy and Materials Processes - Particle Science and Technology (EMPI-PST), University of Duisburg-Essen, Duisburg 47057, Germany.
Center for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Duisburg 47057, Germany.
ACS Omega. 2024 Sep 5;9(37):39253-39258. doi: 10.1021/acsomega.4c06850. eCollection 2024 Sep 17.
Analytical centrifugation is a powerful technique that leverages the principles of centrifugal force and optical detection to characterize emulsion droplets in a label-free and high-throughput manner. Other advantages include minimal sample preparation effort and compatibility with a wide range of emulsion formulations. However, the resulting data can be rather complex and, thus, difficult to fully understand and interpret. To tackle this, we developed two analytical methodologies that enable an easy and intuitive understanding of the data as well as an objective, quantitative analysis and validated them using six model emulsions employing different surfactants. Through their application, insights with unprecedented clarity into dynamic emulsion behavior, stability mechanisms, and emulsion-based processes can be gained, facilitating advancements in fields such as food science, pharmaceuticals, and materials engineering.
分析离心是一种强大的技术，它利用离心力和光学检测原理，以无标记且高通量的方式表征乳液滴。其他优点包括样品制备工作量最小以及与多种乳液配方兼容。然而，所得数据可能相当复杂，因此难以完全理解和解释。为了解决这个问题，我们开发了两种分析方法，能够轻松直观地理解数据，并进行客观的定量分析，并使用六种采用不同表面活性剂的模型乳液对其进行了验证。通过它们的应用，可以以前所未有的清晰度深入了解乳液的动态行为、稳定性机制和基于乳液的过程，促进食品科学、制药和材料工程等领域的进步。
