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手性立方烷类似物的简化命名法和投影图

Simplified Nomenclature and Projection Diagrams of Chiral Cubane Analogs.

作者信息

Krstenansky John L

机构信息

Keck Graduate Institute, School of Pharmacy, 535 Watson Drive, Claremont, California 91711, United States.

出版信息

ACS Omega. 2024 Sep 6;9(37):38629-38632. doi: 10.1021/acsomega.4c04267. eCollection 2024 Sep 17.

Abstract

A simplified nomenclature for chiral cubane analogs is proposed where analogs with a clockwise systematic continuous numbering of the cubane core are designated as ()-, and analogs with an anticlockwise continuous numbering of the cubane core are designated as ()-. This method is accurate, allows for the rapid conversion of the chemical name to a structure, and it eliminates the need to designate the stereochemistry of each of the 8 carbons of cubane.

摘要

提出了一种手性立方烷类似物的简化命名法,其中立方烷核心具有顺时针系统连续编号的类似物被指定为()-,而立方烷核心具有逆时针连续编号的类似物被指定为()-。该方法准确,能使化学名称快速转化为结构,并且无需指定立方烷8个碳原子中每个碳原子的立体化学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0093/11411652/25bb03e80ad2/ao4c04267_0001.jpg

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