Krstenansky John L
Keck Graduate Institute, School of Pharmacy, 535 Watson Drive, Claremont, California 91711, United States.
ACS Omega. 2024 Sep 6;9(37):38629-38632. doi: 10.1021/acsomega.4c04267. eCollection 2024 Sep 17.
A simplified nomenclature for chiral cubane analogs is proposed where analogs with a clockwise systematic continuous numbering of the cubane core are designated as ()-, and analogs with an anticlockwise continuous numbering of the cubane core are designated as ()-. This method is accurate, allows for the rapid conversion of the chemical name to a structure, and it eliminates the need to designate the stereochemistry of each of the 8 carbons of cubane.
提出了一种手性立方烷类似物的简化命名法,其中立方烷核心具有顺时针系统连续编号的类似物被指定为()-,而立方烷核心具有逆时针连续编号的类似物被指定为()-。该方法准确,能使化学名称快速转化为结构,并且无需指定立方烷8个碳原子中每个碳原子的立体化学。