Farzam Ramin, Azad Mohammad Hasan, Moghaddam Hamid Abrishami, Forouzanfar Mohamad
IEEE Trans Biomed Eng. 2025 Feb;72(2):619-629. doi: 10.1109/TBME.2024.3465663. Epub 2025 Jan 21.
Our study aims to advance noninvasive blood pressure (BP) monitoring through the introduction of innovative beat-to-beat oscillometric BP estimation methods. We aim to overcome current device limitations by delivering continuous and accurate BP estimates, utilizing physiologically based mathematical models.
We developed novel beat-to-beat oscillometric BP estimation methods based on physiologically grounded mathematical models of intra-arterial BP and the arterial system effect. Our approach includes a recursive Bayesian method for parameter estimation and a new system identification technique to refine initial parameter estimates. We tested our methods through simulations and real-world experiments involving 10 individuals.
Mean errors for systolic and diastolic BP were as low as -1.26 mmHg and 2.03 mmHg, respectively, with standard deviations of errors at 5.95 mmHg and 4.16 mmHg. Furthermore, our methods enabled the estimation of additional cardiovascular parameters such as heart rate, respiration rate, and mean arterial pressure.
Our novel beat-to-beat oscillometric BP estimation methods offer a significant advancement in noninvasive BP monitoring technology, addressing the limitations of current devices by providing continuous beat-to-beat BP estimates.
Our approach represents a promising direction for improving the reliability and comprehensiveness of cardiovascular parameter estimation in noninvasive BP monitoring devices, facilitating more effective patient care and monitoring.
我们的研究旨在通过引入创新的逐搏示波血压估计方法来推进无创血压(BP)监测。我们旨在通过利用基于生理学的数学模型提供连续且准确的血压估计值,从而克服当前设备的局限性。
我们基于动脉内血压和动脉系统效应的生理学数学模型开发了新颖的逐搏示波血压估计方法。我们的方法包括用于参数估计的递归贝叶斯方法和用于细化初始参数估计的新系统识别技术。我们通过模拟和涉及10名个体的实际实验对我们的方法进行了测试。
收缩压和舒张压的平均误差分别低至-1.26 mmHg和2.03 mmHg,误差的标准差分别为5.95 mmHg和4.16 mmHg。此外,我们的方法能够估计其他心血管参数,如心率、呼吸频率和平均动脉压。
我们新颖的逐搏示波血压估计方法在无创血压监测技术方面取得了重大进展,通过提供连续的逐搏血压估计值解决了当前设备的局限性。
我们的方法代表了一个有前景的方向,可提高无创血压监测设备中心血管参数估计的可靠性和全面性,促进更有效的患者护理和监测。