[Production of secalonic acid D by strains of Penicillium oxalicum and its toxic effects on chick embryos].

Over the years 1983 to 1984, eight strains of Penicillium oxalicum were isolated from feed mixtures for chickens; all of them produced on wheat secalonic acid D (1 to 22 mg X kg-1). As found out, toxic dose of secalonic acid D for two-day, three--day and four-day chicken embryos is 0.90, 2.80 and 3.80 micrograms, respectively. Teratogenic effects, microophthalmia and bilateral beak fissure was observed in the embryotoxicity range on all days of application.