Yuan Mina, Tincher Isabella M, Rojas Danielle A, Sachdeva Bhanvi, Abukhadra Sabine, DeForge Christine E, Flanary Kristin, Chang Bernard P, Agarwal Sachin
Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Department of Neurology, Division of Critical Care and Hospitalist Neurology, Columbia University Irving Medical Center/New York Presbyterian Hospital, Milstein Hospital, 177 Fort Washington Avenue, 8GS-300, New York, NY, 10032, USA.
Neurocrit Care. 2025 Apr;42(2):440-449. doi: 10.1007/s12028-024-02131-x. Epub 2024 Sep 23.
The perception of having poor social support is associated with worse symptoms of psychological distress in close family members of critically ill patients, yet this has never been tested after cardiac arrest.
Close family members of consecutive patients with cardiac arrest hospitalized at an academic tertiary care center participated in a prospective study. The validated Multidimensional Scale of Perceived Social Support (MSPSS) cued to index hospitalization was administered before discharge. Multivariate linear regressions estimated the associations between the total MSPSS score and total scores on the Patient Health Questionnaire-8 (PHQ-8), Generalized Anxiety Disorder 2-item (GAD-2), and the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5), assessed 1 month after cardiac arrest.
In 102 participants (mean age 52 ± 15 years, 70% female, 21% Black, 33% Hispanic) with complete data, the prevalence of depression, generalized anxiety, and probable posttraumatic stress disorder at a median duration of 28.5 days (interquartile range 10-63 days) from cardiac arrest was 61%, 34%, and 13%, respectively. A lower MSPSS score was significantly associated with higher PHQ-8 scores (β = - 0.11 [95% confidence interval - 0.04 to - 0.18]; p < 0.01), even after adjusting for family members' age, sex, prior psychiatric condition, and witnessing of cardiopulmonary resuscitation and patient's discharge disposition (β = - 0.11 [95% confidence interval - 0.02 to - 0.15]; p < 0.01). Similarly, significant inverse associations of total MSPSS scores were seen with 1-month GAD-2 and PCL-5 scores.
Poor social support during hospitalization, as perceived by close family members of cardiac arrest survivors, is associated with worse depressive symptoms at 1 month. Temporal changes in social networks and psychological distress warrant further investigation.
在重症患者的亲密家庭成员中,对社会支持不足的感知与更严重的心理困扰症状相关,但心脏骤停后尚未对此进行过测试。
在一家学术性三级医疗中心住院的连续心脏骤停患者的亲密家庭成员参与了一项前瞻性研究。在出院前使用经过验证的感知社会支持多维量表(MSPSS),该量表以住院指数为提示。多变量线性回归估计了MSPSS总分与患者健康问卷-8(PHQ-8)、广泛性焦虑障碍2项量表(GAD-2)以及创伤后应激障碍检查表(PCL-5)总分之间的关联,这些量表在心脏骤停后1个月进行评估。
在102名有完整数据的参与者(平均年龄52±15岁,70%为女性,21%为黑人,33%为西班牙裔)中,心脏骤停后中位时长28.5天(四分位间距10 - 63天)时,抑郁症、广泛性焦虑症和可能的创伤后应激障碍的患病率分别为61%、34%和13%。较低的MSPSS得分与较高的PHQ-8得分显著相关(β = -0.11[95%置信区间 -0.04至 -0.18];p < 0.01),即使在调整了家庭成员的年龄、性别、既往精神状况、是否目睹心肺复苏以及患者的出院处置情况后也是如此(β = -0.11[95%置信区间 -0.02至 -0.15];p < 0.01)。同样,MSPSS总分与1个月时的GAD-2和PCL-5得分存在显著的负相关。
心脏骤停幸存者的亲密家庭成员所感知到的住院期间社会支持不足与1个月时更严重的抑郁症状相关。社会网络和心理困扰的时间变化值得进一步研究。