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黄斑裂孔自体视网膜移植手术供体区域的光学相干断层扫描特征

OCT Features of the Donor Area in Autologous Retinal Transplant Surgery for Macular Hole.

作者信息

Medina-Medina Silvia, Ramírez-Estudillo Abel, Rojas Juárez Sergio

机构信息

Hospital Nuestra Señora de la Luz, IAP, Ciudad de México, México.

出版信息

J Vitreoretin Dis. 2024 Jul 27;8(5):593-596. doi: 10.1177/24741264241264077. eCollection 2024 Sep-Oct.

DOI:10.1177/24741264241264077
PMID:39318982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11418661/
Abstract

To describe the structural features of the autologous retinal transplant donor tissue area seen on optical coherence tomography (OCT). This observational prospective study included patients who had vitrectomy and autologous retinal graft surgery for a macular hole. OCT of the donor area was performed in the postoperative period after gas reabsorption (mean, 16.2 days ±9.8 [SD] after surgery; range, 7 to 28 days), and structural findings in the harvest area were recorded and analyzed. Of the 12 eyes included in the series, most showed glial tissue or some migration of the inner nuclear layer (INL) in the donor area. Hyperreflective dots and epiretinal membranes were present in a few cases; 2 eyes showed denuded retinal epithelial pigment. OCT revealed changes in the donor area, predominantly filled with glial tissue, INL migration, and inflammatory signs, that mostly resolved during follow-up.

摘要

描述光学相干断层扫描(OCT)上所见的自体视网膜移植供体组织区域的结构特征。这项观察性前瞻性研究纳入了因黄斑裂孔接受玻璃体切除术和自体视网膜移植手术的患者。在气体吸收后的术后阶段(术后平均16.2天±9.8[标准差];范围7至28天)对供体区域进行OCT检查,并记录和分析取材区域的结构发现。该系列纳入的12只眼中,大多数在供体区域显示神经胶质组织或内核层(INL)的一些迁移。少数病例出现高反射点和视网膜前膜;2只眼显示视网膜上皮色素脱失。OCT显示供体区域有变化,主要为神经胶质组织填充、INL迁移和炎症迹象,这些在随访期间大多消退。

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本文引用的文献

1
Surgical classification for large macular hole: based on different surgical techniques results: the CLOSE study group.大黄斑裂孔的手术分类:基于不同手术技术的结果:CLOSE研究组
Int J Retina Vitreous. 2023 Jan 30;9(1):4. doi: 10.1186/s40942-022-00439-4.
2
Update on surgical management of complex macular holes: a review.复杂黄斑裂孔手术治疗的最新进展:综述
Int J Retina Vitreous. 2021 Dec 20;7(1):75. doi: 10.1186/s40942-021-00350-4.
3
Human amniotic membrane for the treatment of large and refractory macular holes: a retrospective, multicentric, interventional study.人羊膜治疗大的难治性黄斑裂孔:一项回顾性、多中心、干预性研究。
Int J Retina Vitreous. 2021 May 8;7(1):38. doi: 10.1186/s40942-021-00308-6.
4
Autologous full-thickness retinal transplant for refractory large macular holes.自体全层视网膜移植治疗难治性大黄斑裂孔
Int J Retina Vitreous. 2020 Nov 23;6(1):60. doi: 10.1186/s40942-020-00266-5.
5
Autologous Retinal Transplantation for Primary and Refractory Macular Holes and Macular Hole Retinal Detachments: The Global Consortium.自体视网膜移植治疗原发性和难治性黄斑裂孔及黄斑裂孔性视网膜脱离:全球联盟。
Ophthalmology. 2021 May;128(5):672-685. doi: 10.1016/j.ophtha.2020.10.007. Epub 2020 Oct 10.
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Literature Review of Surgical Treatment in Idiopathic Full-Thickness Macular Hole.特发性全层黄斑裂孔手术治疗的文献综述
Clin Ophthalmol. 2020 Jul 30;14:2171-2183. doi: 10.2147/OPTH.S262877. eCollection 2020.
7
The Manchester Large Macular Hole Study: Is it Time to Reclassify Large Macular Holes?《曼彻斯特大黄斑裂孔研究:是否到了重新分类大黄斑裂孔的时候?》
Am J Ophthalmol. 2018 Nov;195:36-42. doi: 10.1016/j.ajo.2018.07.027. Epub 2018 Jul 30.
8
Autologous Neurosensory Retinal Free Flap for Closure of Refractory Myopic Macular Holes.自体神经感觉视网膜游离皮瓣用于闭合难治性近视性黄斑裂孔
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