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中国教师血脂异常患病率的系统评价和荟萃分析。

Prevalence of dyslipidemia among teachers in China: a systematic review and meta-analysis.

机构信息

School of Medicine, Macau University of Science and Technology, Macau, China.

The Seventh Affiliated Hospital of Southern Medical University, Foshan, China.

出版信息

Front Public Health. 2024 Aug 27;12:1425387. doi: 10.3389/fpubh.2024.1425387. eCollection 2024.

Abstract

OBJECTIVE

To systematically analyze the current situation with dyslipidemia among teachers in China, to provide guidance for lipid management and prevention of ASCVD.

DESIGN

A systematic review and meta-analysis of the prevalence of dyslipidemia among teachers in China.

METHODS

We searched via 9 databases for studies published between June 1, 1996, and July, 25, 2024. The article were evaluated by the Joanna Briggs Institute (JBI) Article Quality Assessment Tool (2016) in Australia. RevMan5.0 and R4.3.1 software were used for statistical analysis to calculate the OR and RR values and the 95% confidence intervals. This systematic review and meta-analysis were reported in line with the PRISMA guidelines.

RESULTS

A total of 12 cross-sectional studies from 10 provinces (regions) were included, with the sample of 24,851, including 12,626 males and 12,198 females, the average age of about 40 (1,036 were aged ≤30, 5,872 were aged 30-40, 3,854 were aged 40-50, 4,607 were aged 50-60, and 3,425 were aged ≥60), including 9,114 people with dyslipidemia. The overall prevalence of dyslipidemia among teachers in China was 38% ( < 0.01, 95% CI (1.27-1.95)). The prevalence of hypertriglyceridemia was 21.6% ( < 0.01, 95% CI (1.05-1.50)), that of hypercholesterolemia was 13.3% ( < 0.05, 95% CI (0.98-1.34)), that of hyper-LDL-Cemia was 9.4% ( < 0.01, 95% CI (1.04-1.59)), and that of hypo-HDL-Cemia was 4.3% ( = 0.25, 95% CI (0.61-6.52)). The heterogeneity of dyslipidemia among teachers of the different sexes was I = 92% ( < 0.01). The overall prevalence of dyslipidemia, as well as that of high TC, high TG, and high LDL-C levels, was greater in female teachers than in male teachers (df = 10, 95% CI:1.35-1.52,  < 0.01). The heterogeneity of dyslipidemia among teachers of different ages was I = 74% ( < 0.01), and the risk was lower for aged <50 years than those aged ≥50 years (df = 7, 95% CI: 0.38-0.44,  = 0.04). The year, region, school type, and these factors showed no effect on the prevalence of dyslipidemia ( = 0.7353).

CONCLUSION

The prevalence of dyslipidemia in the teacher population in China is high and tends to increase with age. We should pay attention to the health management of the teachers, which can be done by appropriately adjusting the educational model settings, increasing the programs on physical activities, promoting the improvement of healthy lifestyles.

SYSTEMATIC REVIEW REGISTRATION

https://www.crd.york.ac.uk/prospero/, identifier [CRD42024567785].

摘要

目的

系统分析中国教师血脂异常的现状,为血脂管理和 ASCVD 预防提供指导。

设计

对中国教师血脂异常患病率的系统评价和荟萃分析。

方法

我们检索了 1996 年 6 月 1 日至 2024 年 7 月 25 日期间发表的 9 个数据库的研究。使用澳大利亚的 Joanna Briggs 研究所(JBI)文章质量评估工具(2016 年)对文章进行评估。使用 RevMan5.0 和 R4.3.1 软件进行统计分析,计算 OR 和 RR 值及其 95%置信区间。本系统评价和荟萃分析符合 PRISMA 指南。

结果

共纳入来自 10 个省(区)的 12 项横断面研究,样本量为 24851 人,包括 12626 名男性和 12198 名女性,平均年龄约为 40 岁(1036 人年龄≤30 岁,5872 人年龄 30-40 岁,3854 人年龄 40-50 岁,4607 人年龄 50-60 岁,3425 人年龄≥60 岁),其中 9114 人患有血脂异常。中国教师血脂异常总体患病率为 38%( < 0.01,95%CI(1.27-1.95))。高甘油三酯血症的患病率为 21.6%( < 0.01,95%CI(1.05-1.50)),高胆固醇血症的患病率为 13.3%( < 0.05,95%CI(0.98-1.34)),高 LDL-C 血症的患病率为 9.4%( < 0.01,95%CI(1.04-1.59)),低 HDL-C 血症的患病率为 4.3%( = 0.25,95%CI(0.61-6.52))。不同性别教师血脂异常的异质性为 I = 92%( < 0.01)。女教师血脂异常、高 TC、高 TG 和高 LDL-C 水平的总体患病率均高于男教师(df = 10,95%CI:1.35-1.52, < 0.01)。不同年龄教师血脂异常的异质性为 I = 74%( < 0.01),年龄<50 岁的风险低于年龄≥50 岁的风险(df = 7,95%CI:0.38-0.44, = 0.04)。年份、地区、学校类型以及这些因素对血脂异常的患病率均无影响( = 0.7353)。

结论

中国教师人群血脂异常的患病率较高,且有随年龄增长而增加的趋势。我们应关注教师的健康管理,可以通过适当调整教育模式设置、增加体育活动项目、促进健康生活方式的改善来实现。

系统评价注册

https://www.crd.york.ac.uk/prospero/,标识符[CRD42024567785]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa01/11421384/924b4d7254b5/fpubh-12-1425387-g001.jpg

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