Zabka J, Stríbrná J, Korandová V, Tschernoster E, Matousovic K
Czech Med. 1985;8(3):144-50.
A group of 198 renal transplantations performed et our Centre in 1976-1981 was evaluated. Arterial hypertension within the first two weeks following transplantation developed in 83% of patients, in 43% being severe. Later, towards the end of the first year, less patients suffered from arterial hypertension, especially of severe hypertension. In this period, hypertension occurred in about 63%, in most cases in the mild form (50%). Patients with graft functioning for more than a year had hypertension, mostly mild, in about 43%. The incidence of hypertension in our group was, however, increased if "normotensives" taking antihypertensives were included. We may conclude that in the first year following renal transplantation true normotensive patients formed approximately 10% of the total and their number in the subsequent years raised up to 50%. The values of blood pressure in the 3rd to 4th months had a predictive significance for the further course of hypertension. In this period, patients with hypertension had a markedly worse cumulative graft survival compared with the remaining subjects. This finding supports the importance of energetic antihypertensive therapy.
对1976年至1981年在我们中心进行的198例肾移植手术进行了评估。移植后前两周内,83%的患者出现动脉高血压,其中43%为重度高血压。后来,在第一年末,患动脉高血压的患者减少,尤其是重度高血压患者。在此期间,高血压发生率约为63%,大多数为轻度形式(50%)。移植肾功能超过一年的患者中,约43%患有高血压,大多为轻度。然而,如果将服用抗高血压药物的“血压正常者”包括在内,我们组中高血压的发生率会增加。我们可以得出结论,在肾移植后的第一年,真正血压正常的患者约占总数的10%,而在随后几年中这一比例上升至50%。第3至4个月的血压值对高血压的进一步发展具有预测意义。在此期间,高血压患者的移植肾累积存活率明显低于其他患者。这一发现支持了积极抗高血压治疗的重要性。