2018-2023 年法国产耐苯唑西林酶 484 的肠杆菌科细菌。

Emerg Infect Dis. 2024 Oct;30(10):2178-2182. doi: 10.3201/eid3010.240814.

We examined the emergence and characteristics of oxacillinase-484-producing Enterobacterales in France during 2012-2023. Genomic analysis identified 2 predominant sequence types in Escherichia coli: ST410 and ST1722. Plasmid analysis revealed that bla genes were carried mostly on an IncX3-type plasmid associated with genetic elements including insertion sequences IS3000 and ISKpn19.

我们研究了 2012 年至 2023 年期间法国产耐苯唑西林-484 型肠杆菌科细菌的出现和特征。基因组分析鉴定出大肠杆菌中两种主要的序列类型：ST410 和 ST1722。质粒分析显示，bla 基因主要携带在与插入序列 IS3000 和 ISKpn19 等遗传元件相关的 IncX3 型质粒上。