Slaughter Alexander W, Stiver Jordan, Savin Micah, Oleas Denise S, Lee Hyunjung, Summers Angela, Zhu Danqi, Cham Heining, Robinson-Papp Jessica, Mindt Monica Rivera
Alexander W. Slaughter, BS, is a Clinical Research Coordinator, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Jordan Stiver, PhD, is a Postdoctoral Fellow, University of California, San Diego, San Diego, California, USA. Micah Savin, PhD, is a Postdoctoral Fellow, Columbia University, New York, New York, USA. Denise S. Oleas, MA, is a Doctoral Student, Fordham University, Bronx, New York, USA. Hyunjung Lee, MA, is a Doctoral Student, Fordham University, Bronx, New York, USA. Angela Summers, PhD, is a Postdoctoral Fellow, DC Veterans Affairs Medical Center, Washington, District of Columbia, USA. Danqi Zhu, MA, is a Doctoral Student, Fordham University, Bronx, New York, USA. Heining Cham, PhD, is an Associate Professor, Fordham University, Bronx, New York, USA. Jessica Robinson-Papp, MD, MS, is Vice Chair of Research, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Monica Rivera Mindt, PhD, ABPP-CN, is a Professor, Fordham University, Bronx, New York, USA and Icahn School of Medicine at Mount Sinai, New York, New York, USA.
J Assoc Nurses AIDS Care. 2025;36(1):69-80. doi: 10.1097/JNC.0000000000000504. Epub 2024 Sep 25.
Stress and HIV disproportionately affect Latinx adults in the United States, contributing to numerous health inequities. Among people living with HIV (PLWH), increased stress is associated with decreased medication adherence, effectiveness, and higher rates of immunosuppression and comorbidities. Our study ( N = 126) examined the relationship between perceived stress and HIV-related health among Latinx ( n = 83) and non-Latinx White ( n = 43) PLWH. Latinx PLWH reported better HIV-related health outcomes than non-Latinx White PLWH, despite higher viral load (all p 's < .05). An interaction effect showed that higher perceived distress was associated with worse health outcomes and lower CD4+ T cell count only in Latinx PLWH ( p 's < .05). Our findings highlight the consequences of stress on HIV-related health. Notably, higher stress may be especially detrimental among Latinx PLWH, underscoring the need for more culturally tailored interventions in HIV-related care. Future research should include additional sociocultural factors and longitudinal assessment in a larger sample.
压力和艾滋病毒对美国的拉丁裔成年人影响尤为严重，导致了众多健康不平等问题。在艾滋病毒感染者（PLWH）中，压力增加与药物依从性降低、疗效下降以及免疫抑制和合并症发生率升高有关。我们的研究（N = 126）调查了拉丁裔（n = 83）和非拉丁裔白人（n = 43）艾滋病毒感染者中感知压力与艾滋病毒相关健康之间的关系。尽管病毒载量较高（所有p值 <.05），但拉丁裔艾滋病毒感染者报告的艾滋病毒相关健康结果比非拉丁裔白人艾滋病毒感染者更好。交互作用效应表明，仅在拉丁裔艾滋病毒感染者中，较高的感知痛苦与较差的健康结果和较低的CD4 + T细胞计数相关（p值 <.05）。我们的研究结果突出了压力对艾滋病毒相关健康的影响。值得注意的是，较高的压力可能对拉丁裔艾滋病毒感染者尤其有害，这凸显了在艾滋病毒相关护理中需要更多针对文化特点的干预措施。未来的研究应纳入更多社会文化因素，并在更大样本中进行纵向评估。
