Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, Brown University, Providence, RI, United States.
Providence Veterans Affairs Medical Center, Providence, RI, United States.
JMIR Res Protoc. 2024 Sep 25;13:e58685. doi: 10.2196/58685.
There is significant conflicting evidence as to how using cannabis while drinking alcohol (ie, simultaneous alcohol and cannabis use) impacts alcohol volume consumed, patterns of drinking, and alcohol-related consequences. The impact of simultaneous use on drinking outcomes may be influenced by several within-person (eg, contextual) and between-person (individual) factors.
This study was designed to examine naturalistic patterns of alcohol and cannabis use to understand how simultaneous use may impact drinking outcomes. The primary aims were to understand the following: (1) if simultaneous use is associated with increased alcohol consumption and riskier patterns of drinking, (2) if simultaneous use leads to increased alcohol consequences, and (3) how contextual circumstances moderate the impact of simultaneous use on consumption and consequences.
Data collection involves a 28-day ambulatory assessment protocol in which a sample of non-treatment-seeking young adults who report simultaneous use of alcohol and cannabis complete ecological momentary assessments (random, event-contingent, and time-contingent surveys) of alcohol and cannabis use, contexts, motives, and consequences on their personal smartphones while continuously wearing an alcohol biosensor bracelet. Participants also complete a baseline assessment, brief internet-based check-in on day 14, and a final session on day 28. Community-based recruitment strategies (eg, social media and flyers) were used to enroll 95 participants to obtain a target sample of 80, accounting for attrition.
Recruitment and data collection began in May 2021 and continued through June 2024. Initial results for primary aims are expected in October 2024. As of March 2024, the project had recruited 118 eligible participants, of whom 94 (79.7%) completed the study, exceeding initial projections for the study time frame. Remaining recruitment will provide the capacity to probe cross-level interactions that were not initially statistically powered. Strengths of the project include rigorous data collection, good retention and compliance rates, faster-than-expected enrollment procedures, use of a novel alcohol biosensor, and successful adaptation of recruitment and data collection procedures during the COVID-19 pandemic.
This is the first investigation to assess the key momentary predictors and outcomes of simultaneous use as well as self-reported and objective (via alcohol biosensor) measures of alcohol consumption and patterns. The results of this study will inform prevention efforts and studies of individuals who use cannabis who are engaged in alcohol treatment.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/58685.
关于吸食大麻同时饮酒（即同时摄入酒精和大麻）会如何影响摄入的酒精量、饮酒模式和与酒精相关的后果，存在大量相互矛盾的证据。同时使用对饮酒结果的影响可能受到个体内部（例如，情境）和个体之间（个体）因素的影响。
本研究旨在通过观察自然状态下的酒精和大麻使用模式，来了解同时使用可能对饮酒结果产生的影响。主要目的是了解以下几点：（1）同时使用是否与饮酒量增加和更危险的饮酒模式有关，（2）同时使用是否会导致更多的酒精后果，以及（3）情境环境如何调节同时使用对消费和后果的影响。
数据收集涉及 28 天的动态评估方案，在此期间，报告同时使用酒精和大麻的非治疗寻求的年轻成年人样本使用个人智能手机完成酒精和大麻使用、环境、动机和后果的生态瞬间评估（随机、事件相关和时间相关的调查），同时持续佩戴酒精生物传感器手镯。参与者还完成基线评估、第 14 天的简短在线签到和第 28 天的最后一次会议。采用社区招募策略（例如，社交媒体和传单）招募了 95 名参与者，以获得 80 名参与者的目标样本，其中包括流失的参与者。
招募和数据收集于 2021 年 5 月开始，持续到 2024 年 6 月。主要目标的初步结果预计于 2024 年 10 月公布。截至 2024 年 3 月，该项目已经招募了 118 名符合条件的参与者，其中 94 名（79.7%）完成了研究，超过了研究时间框架的最初预测。剩余的招募将提供探测最初没有统计学效力的跨层次相互作用的能力。该项目的优势包括严格的数据收集、良好的保留和遵守率、快于预期的招募程序、使用新型酒精生物传感器，以及在 COVID-19 大流行期间成功调整招募和数据收集程序。
这是首次评估同时使用的关键瞬间预测因素和结果，以及自我报告和客观（通过酒精生物传感器）测量的饮酒量和模式的研究。该研究的结果将为预防工作和从事酒精治疗的吸食大麻者的研究提供信息。
国际注册报告标识符（IRRID）：DERR1-10.2196/58685。
