Meisel Samuel N, Hogue Aaron, Kelly John F, McQuaid Elizabeth, Miranda Robert
Department of Psychological and Brain Sciences, Boston University, Boston, MA, United States.
Partnership to End Addiction, New York, NY, United States.
JMIR Res Protoc. 2024 Dec 20;13:e63399. doi: 10.2196/63399.
Caregiver-involved treatments for adolescents with alcohol use disorder and co-occurring disorders (AUD+CODs) are associated with the best treatment outcomes. Understanding what caregiving practices during treatment improve core adolescent treatment targets may facilitate the refinement and scalability of caregiver-involved interventions. Caregiving is dynamic, varying by context, affect, and adolescent behavior. Caregiver-involved treatments seek to change momentary interactions between caregivers and their adolescents. Accordingly, this protocol outlines a dyadic ecological momentary assessment (EMA) study to examine caregiving practices during AUD+CODs treatment and their associations with adolescent core treatment targets (eg, alcohol craving and use, motivation to reduce or stop drinking, and internalizing and externalizing symptoms).
This paper aims to describe the methods for examining momentary caregiving practices and adolescent core treatment targets during adolescent outpatient AUD+CODs treatment.
We will recruit 75 caregiver-adolescent dyads from outpatient mental health clinics providing AUD+CODs treatment. Eligible families will have an adolescent who (1) is aged between 13 and 18 years; (2) meets the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, diagnostic criteria for AUD; (3) is enrolled in outpatient treatment at the time of recruitment; and (4) has a legal guardian willing to participate in the study. Caregivers and adolescents will complete an eligibility screening, followed by a baseline assessment during or as close as possible to the second week of treatment. During the baseline assessment, caregivers and adolescents will receive formal training in EMA procedures. Next, caregivers and adolescents will complete a 15-week EMA burst design consisting of three 21-day EMA periods with 3-week breaks between periods. Throughout the study, participants will also complete weekly reports regarding the skills learned or practiced during therapy. The three overarching aims to the proposed study are as follows: (1) examine momentary caregiving practices (eg, support, monitoring, substance use communication quality) and their associations with core treatment targets, (2) examine how these associations change throughout treatment, and (3) examine whether a caregiver report of learning or practicing parenting- or family-focused behaviors in treatment sessions is associated with changes in the use of caregiving practices in daily life.
The proposed study was informed by a pilot study assessing the feasibility and acceptability of dyadic EMA during adolescent AUD+COD treatment. Some benchmarks were met during this study (eg, ≥80% caregiver retention rate), although most benchmarks were not (eg, adolescent [772/1622, 47.6%] and caregiver [1331/1881, 70.76%] random prompt compliance was below the ≥80% target). Data collection is anticipated to begin in December of 2024. The proposed study is designed to be completed over 3 years.
Examining momentary caregiving practices using EMA has important implications for refining and scaling caregiver-involved interventions for AUD+CODs so that families who would benefit from caregiver-involved treatments can have access to them.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/63399.
针对患有酒精使用障碍及共病(AUD+CODs)的青少年,由照顾者参与的治疗与最佳治疗效果相关。了解治疗期间的哪些照顾行为能改善青少年的核心治疗目标,可能有助于完善和推广由照顾者参与的干预措施。照顾行为是动态的,会因情境、情感和青少年行为而有所不同。由照顾者参与的治疗旨在改变照顾者与其青少年之间的即时互动。因此,本方案概述了一项二元生态瞬时评估(EMA)研究,以考察AUD+CODs治疗期间的照顾行为及其与青少年核心治疗目标(如酒精渴望与使用、减少或停止饮酒的动机以及内化和外化症状)之间的关联。
本文旨在描述在青少年门诊AUD+CODs治疗期间,考察即时照顾行为和青少年核心治疗目标的方法。
我们将从提供AUD+CODs治疗的门诊心理健康诊所招募75对照顾者-青少年二元组。符合条件的家庭中,青少年需满足以下条件:(1)年龄在13至18岁之间;(2)符合《精神疾病诊断与统计手册》第五版中酒精使用障碍的诊断标准;(3)在招募时正在接受门诊治疗;(4)有愿意参与研究的法定监护人。照顾者和青少年将完成资格筛选,随后在治疗的第二周或尽可能接近第二周时进行基线评估。在基线评估期间,照顾者和青少年将接受EMA程序的正式培训。接下来,照顾者和青少年将完成一个为期15周的EMA突发设计,包括三个为期21天的EMA阶段,各阶段之间有3周的休息时间。在整个研究过程中,参与者还将每周报告在治疗期间学到或实践的技能。本研究的三个总体目标如下:(1)考察即时照顾行为(如支持、监督、物质使用沟通质量)及其与核心治疗目标的关联;(2)考察这些关联在整个治疗过程中的变化;(3)考察照顾者报告在治疗 session 中学习或实践以父母或家庭为重点的行为是否与日常生活中照顾行为的使用变化相关。
本研究方案参考了一项评估青少年AUD+COD治疗期间二元EMA可行性和可接受性的试点研究。在这项研究中达到了一些基准(如照顾者保留率≥80%),尽管大多数基准未达到(如青少年[<80%,772/1622,47.6%]和照顾者[<80%,1331/1881,70.76%]随机提示依从性低于≥80%的目标)。预计数据收集将于2024年12月开始。本研究方案设计为在3年内完成。
使用EMA考察即时照顾行为对于完善和推广针对AUD+CODs的由照顾者参与的干预措施具有重要意义,以便那些将从由照顾者参与的治疗中受益的家庭能够获得此类治疗。
国际注册报告识别号(IRRID):PRR1-10.2196/63399 。