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无线光泵磁强计 MEG。

Wireless optically pumped magnetometer MEG.

机构信息

Center for MRl Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, PR China; Changping Laboratory, Beijing 102206, PR China.

Changping Laboratory, Beijing 102206, PR China.

出版信息

Neuroimage. 2024 Oct 15;300:120864. doi: 10.1016/j.neuroimage.2024.120864. Epub 2024 Sep 24.

Abstract

The current magnetoencephalography (MEG) systems, which rely on cables for control and signal transmission, do not fully realize the potential of wearable optically pumped magnetometers (OPM). This study presents a significant advancement in wireless OPM-MEG by reducing magnetization in the electronics and developing a tailored wireless communication protocol. Our protocol effectively eliminates electromagnetic interference, particularly in the critical frequency bands of MEG signals, and accurately synchronizes the acquisition and stimulation channels with the host computer's clock. We have successfully achieved single-channel wireless OPM-MEG measurement and demonstrated its reliability by replicating three well-established experiments: The alpha rhythm, auditory evoked field, and steady-state visual evoked field in the human brain. Our prototype wireless OPM-MEG system not only streamlines the measurement process but also represents a major step forward in the development of wearable OPM-MEG applications in both neuroscience and clinical research.

摘要

当前的脑磁图(MEG)系统依赖于电缆进行控制和信号传输,无法充分发挥可穿戴式光泵磁力计(OPM)的潜力。本研究通过降低电子设备中的磁化强度并开发定制的无线通信协议,在无线 OPM-MEG 方面取得了重大进展。我们的协议有效地消除了电磁干扰,特别是在 MEG 信号的关键频段内,并且可以与主机计算机的时钟精确地同步采集和刺激通道。我们已经成功地实现了单通道无线 OPM-MEG 测量,并通过复制三个成熟的实验:人类大脑中的 alpha 节律、听觉诱发场和稳态视觉诱发场,证明了其可靠性。我们的原型无线 OPM-MEG 系统不仅简化了测量过程,而且代表了可穿戴式 OPM-MEG 在神经科学和临床研究中的应用开发方面的重要进展。

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