Department of Nutrition, An-Najah National University Hospital, Nablus, 44839, Palestine.
Department of Public Health, College of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.
Support Care Cancer. 2024 Sep 26;32(10):689. doi: 10.1007/s00520-024-08879-4.
Many cancer patients experience malnutrition, which can worsen their health and survival outcomes. However, limited research exists in our region on how common malnutrition is among hospitalized adults with solid tumors and what factors contribute to it. This study aimed to identify these factors and assess the effects of nutritional impact symptoms (NISs) caused by solid tumors on patients' nutritional status.
Between July 2022 and February 2023, a cross-sectional study was carried out on the campuses of two major cancer treatment centers located in a national university hospital and a governmental hospital. Twelve NISs were adopted from the Patient-Generated Subjective Global Assessments (PG-SGA). The Nutrition Risk Screening 2002 (NRS-2002) instrument was used to thoroughly assess the risk of malnutrition. Multiple linear regressions were used to conduct a thorough study.
A cohort of 294 participants was included. The prevalence of malnutrition risk (NRS score ≥ 3) was 26.9%. Parameters such as age, gender, marital status, educational level, monthly income, type of cancer and treatment modality, and the need for mealtime assistance exhibited statistically significant associations with malnutrition (p < 0.05). The results revealed a substantial inverse correlation between fluid intake and the NRS-2002 score (p < 0.001). Furthermore, symptoms related to solid tumors and their treatment, including chewing difficulties, fatigue, dry mouth, anorexia, constipation, nausea, dizziness, and a sensation of fullness, were also significantly associated with malnutrition (p < 0.05). Additional insights from the regression analysis underscored the independent correlation between the risk of malnutrition in solid malignant malignancies and factors such as anorexia (p < 0.001), colorectal cancer (p = 0.003), gender (p = 0.018), educational attainment (p = 0.049), and the need for mealtime assistance among patients (p < 0.001).
Malnutrition is a major issue among adult cancer patients, particularly those with solid tumors. Anorexia, colorectal cancer, gender, educational attainment, and the need for mealtime assistance were identified as factors that led to malnutrition in our research. This study emphasizes the need for a multidisciplinary plan of care to diagnose and treat malnutrition, improve overall therapy, and reduce mortality and morbidity.
许多癌症患者存在营养不良，这会使他们的健康状况和生存结果恶化。然而，在我们所在地区，关于住院实体瘤成年患者中营养不良的普遍程度以及导致营养不良的因素，相关研究十分有限。本研究旨在确定这些因素，并评估实体瘤引起的营养影响症状（NISs）对患者营养状况的影响。
2022 年 7 月至 2023 年 2 月，在一家国立大学医院和一家政府医院的两个主要癌症治疗中心的校园内进行了一项横断面研究。采用来自患者生成主观整体评估（PG-SGA）的 12 种 NIS。使用营养风险筛查 2002 （NRS-2002）工具对营养不良风险进行全面评估。采用多元线性回归进行深入研究。
共纳入 294 名参与者。营养不良风险（NRS 评分≥3）的患病率为 26.9%。年龄、性别、婚姻状况、教育程度、月收入、癌症类型和治疗方式以及对用餐帮助的需求等参数与营养不良显著相关（p<0.05）。结果显示，液体摄入量与 NRS-2002 评分呈显著负相关（p<0.001）。此外，与实体瘤及其治疗相关的症状，包括咀嚼困难、疲劳、口干、厌食、便秘、恶心、头晕和饱腹感，也与营养不良显著相关（p<0.05）。回归分析的进一步结果强调了实体恶性肿瘤患者的营养不良风险与厌食症（p<0.001）、结直肠癌（p=0.003）、性别（p=0.018）、教育程度（p=0.049）和患者对用餐帮助的需求等因素之间的独立相关性。
营养不良是成年癌症患者的一个主要问题，特别是那些患有实体瘤的患者。厌食症、结直肠癌、性别、教育程度和对用餐帮助的需求是导致我们研究中患者营养不良的因素。本研究强调需要多学科护理计划来诊断和治疗营养不良，改善整体治疗效果，并降低死亡率和发病率。
