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头颈部癌多学科治疗联合动脉内化疗的评估

[An evaluation of multi-disciplinary treatment combined with intra-arterial chemotherapy of head and neck cancer].

作者信息

Matsuura S, Makino S, Satake B, Shimizu R, Sakaino K, Maehara Y, Nakamura Y, Miyama J

出版信息

Gan No Rinsho. 1985 Jul;31(9 Suppl):1057-62.

PMID:3932709
Abstract

Seventy-five cases of head and neck cancer except of maxillary sinus, 27 cases of mesopharyngeal cancer, 6 cases of oral cancer, 9 cases of thyroid cancer and 9 cases of the other cancer, were treated with this multi-disciplinary treatment and the results were evaluated in this series. An intraarterial infusion drug, 5-FU, was used mainly through the superficial temporal artery. The five year survival rate was 46.1% in mesopharyngeal cancer, 34.4% in oral cancer and 33.3% in thyroid cancer. The results were relatively satisfactory despite the advanced stage of the cancer. Intraarterial chemotherapy has been a common treatment for maxillary cancer but the indication of this treatment should be developed in advanced head and neck cancer with radiotherapy or surgical treatment as a part of multi-disciplinary treatment.

摘要

除上颌窦癌外的75例头颈部癌、27例鼻咽癌、6例口腔癌、9例甲状腺癌和9例其他癌症,接受了这种多学科治疗,并对该系列结果进行了评估。主要通过颞浅动脉使用动脉内灌注药物5-氟尿嘧啶。鼻咽癌的五年生存率为46.1%,口腔癌为34.4%,甲状腺癌为33.3%。尽管癌症处于晚期,但结果相对令人满意。动脉内化疗一直是上颌窦癌的常用治疗方法,但这种治疗的适应证应在晚期头颈部癌中发展,将放疗或手术治疗作为多学科治疗的一部分。

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