Department of Medical Ethics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Department of Biomedical Ethics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
J Empir Res Hum Res Ethics. 2024 Oct;19(4-5):208-219. doi: 10.1177/15562646241286143. Epub 2024 Sep 27.
Through strengthened biobank governance, broad consent has been widely accepted as a means to replace donors' discretion based on the information of individual research protocols. Trust and other ethical and social notions, such as reciprocity and solidarity, are key concepts that support biobank governance. The types of allowed broad consent are several; however, they remain unclear, and whether these ethical and social notions are associated with public attitudes toward the consent model is not fully understood. This quantitative study examined two hypotheses: narrower and limited broad consent are more accepted by the public, and acceptance rates for broad consent increase with established measures related to biobank governance. This analysis supported both hypotheses, implying that the limited type of broad consent should be considered an important option, and that a specific type of governance is critical in promoting trust, reciprocity, and solidarity between biobanks and the public.
通过加强生物库治理，广泛同意已被广泛接受为一种取代基于个别研究方案信息的捐赠者自由裁量权的手段。信任和其他伦理和社会概念，如互惠和团结，是支持生物库治理的关键概念。允许的广泛同意类型有几种；然而，它们仍然不清楚，这些伦理和社会概念是否与公众对同意模式的态度有关，这一点还不完全清楚。这项定量研究检验了两个假设：较窄和有限的广泛同意更受公众欢迎，并且随着与生物库治理相关的既定措施的增加，对广泛同意的接受率也会提高。这项分析支持了这两个假设，这意味着有限类型的广泛同意应该被视为一个重要的选择，而特定类型的治理对于促进生物库和公众之间的信任、互惠和团结至关重要。
