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锥束计算机断层扫描引导下针对一名极晚期头颈癌患者的按需在线自适应放射治疗中外轮廓变化的解决方案：技术病例报告

Solution for the External Contour Changes in Cone Beam Computed Tomography-Guided On-demand Online Adaptive Radiotherapy for a Patient With Very Advanced Head and Neck Cancer: A Technical Case Report.

作者信息

Wang Jinyuan, Dai Xiangkun, Qu Baolin, Yan Changxin, Kou Yuhan, Liu Xiaoyu, Wang Xiaoshen, Cai Boning

机构信息

Department of Radiotherapy, The First Medical Center of the Chinese PLA General Hospital, Beijing, CHN.

Clinical Application Training Department, Varian Medical System, Beijing, CHN.

出版信息

Cureus. 2024 Aug 26;16(8):e67804. doi: 10.7759/cureus.67804. eCollection 2024 Aug.

DOI:10.7759/cureus.67804
PMID:39328634
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11424223/
Abstract

This article presents a case of a patient with advanced head and neck cancer, characterized by a large and protruding tumor. The patient was treated with an innovative on-demand online adaptive radiotherapy (ART) technology, guided by cone beam computed tomography (CBCT), on the Ethos adaptive radiotherapy platform (version 1.0, Varian Medical Systems, Palo Alto, CA). A solution was provided for this special case to address the issue where part of the target volume could not participate in the optimization due to exceeding the external contour boundary during online adaptive radiotherapy. The treatment outcome was satisfactory in terms of tumor regression, while only grade 1 radiodermatitis and grade 2 oral mucositis at the end of radiotherapy. This article discusses the clinical diagnosis, treatment process, and follow-up of this case, aiming to provide clinical references for a broader application of this technology.

摘要

本文介绍了一例晚期头颈癌患者，其特征为肿瘤巨大且突出。该患者在Varian Medical Systems公司（位于加利福尼亚州帕洛阿尔托）的Ethos自适应放疗平台（版本1.0）上，接受了以锥形束计算机断层扫描（CBCT）为引导的创新型按需在线自适应放疗（ART）技术治疗。针对这一特殊情况，提供了一种解决方案，以解决在线自适应放疗期间部分靶区因超出外部轮廓边界而无法参与优化的问题。在肿瘤消退方面，治疗结果令人满意，放疗结束时仅出现1级放射性皮炎和2级口腔黏膜炎。本文讨论了该病例的临床诊断、治疗过程及随访情况，旨在为该技术的更广泛应用提供临床参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/ab23469898da/cureus-0016-00000067804-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/f24214e10b5f/cureus-0016-00000067804-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/d2ce5c33255e/cureus-0016-00000067804-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/34d628604f13/cureus-0016-00000067804-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/08a949d90b7e/cureus-0016-00000067804-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/cc87bdfa73a8/cureus-0016-00000067804-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/2ee2fc3d4438/cureus-0016-00000067804-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/ab23469898da/cureus-0016-00000067804-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/f24214e10b5f/cureus-0016-00000067804-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/d2ce5c33255e/cureus-0016-00000067804-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/34d628604f13/cureus-0016-00000067804-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/08a949d90b7e/cureus-0016-00000067804-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/cc87bdfa73a8/cureus-0016-00000067804-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/2ee2fc3d4438/cureus-0016-00000067804-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11ea/11424223/ab23469898da/cureus-0016-00000067804-i07.jpg

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本文引用的文献

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Adapt-On-Demand: A Novel Strategy for Personalized Adaptive Radiation Therapy for Locally Advanced Lung Cancer.按需自适应：局部晚期肺癌个体化自适应放疗的新策略。
Pract Radiat Oncol. 2024 Sep-Oct;14(5):e395-e406. doi: 10.1016/j.prro.2024.02.007. Epub 2024 Apr 4.
2
Real world clinical experience using daily intelligence-assisted online adaptive radiotherapy for head and neck cancer.使用日常智能辅助在线自适应放疗治疗头颈部癌症的真实世界临床经验。
Radiat Oncol. 2024 Mar 30;19(1):43. doi: 10.1186/s13014-024-02436-3.
3
In Silico Analysis of Adjuvant Head and Neck Online Adaptive Radiation Therapy.
头颈部辅助在线自适应放射治疗的计算机模拟分析
Adv Radiat Oncol. 2023 Jul 23;9(1):101319. doi: 10.1016/j.adro.2023.101319. eCollection 2024 Jan.
4
Investigating the feasibility of using Ethos generated treatment plans for head and neck cancer patients.研究对头颈部癌症患者使用Ethos生成的治疗计划的可行性。
Tech Innov Patient Support Radiat Oncol. 2023 Jun 27;27:100216. doi: 10.1016/j.tipsro.2023.100216. eCollection 2023 Sep.
5
Early Experience of Online Adaptive Radiation Therapy for Definitive Radiation of Patients With Head and Neck Cancer.头颈部癌患者确定性放疗的在线自适应放射治疗早期经验
Adv Radiat Oncol. 2023 Apr 26;8(5):101256. doi: 10.1016/j.adro.2023.101256. eCollection 2023 Sep-Oct.
6
Weekly Adaptive Radiotherapy vs Standard Intensity-Modulated Radiotherapy for Improving Salivary Function in Patients With Head and Neck Cancer: A Phase 3 Randomized Clinical Trial.每周自适应放疗与标准强度调制放疗改善头颈部癌症患者唾液功能的比较：一项 3 期随机临床试验。
JAMA Oncol. 2023 Aug 1;9(8):1056-1064. doi: 10.1001/jamaoncol.2023.1352.
7
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Adaptive radiation therapy: When, how and what are the benefits that literature provides?适应性放疗法：何时、如何以及文献提供了哪些益处？
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9
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