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额窦腺癌:一例从内翻性乳头状瘤重新评估诊断的罕见病例。

Frontal Sinus Adenocarcinoma: A Rare Case of Diagnostic Re-evaluation From Inverted Papilloma.

作者信息

Chu Samuel, Husain Salina

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Hospital Ampang, Ampang, MYS.

Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.

出版信息

Cureus. 2024 Aug 26;16(8):e67878. doi: 10.7759/cureus.67878. eCollection 2024 Aug.

DOI:10.7759/cureus.67878
PMID:39328650
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11425026/
Abstract

Adenocarcinoma of the frontal sinus is extremely rare. We present a primary frontal sinus adenocarcinoma masquerading as an inverted papilloma (IP). Here, we reviewed various clinical presentations, investigations, and management of frontal sinus adenocarcinoma. A 48-year-old male presented with nasal bridge swelling one month following endoscopic sinus surgery for frontal sinus inverted papilloma. Progressively enlarging swelling with persistent pressure symptoms drew doubts regarding previously proven diagnosis. Imaging studies put us at the management crossroads of malignancy versus infection (osteomyelitis). The complexity of this case prompted a multidisciplinary team approach, eventually leading to a revision surgery for re-evaluation. Re-excision of the frontal sinus tumor was later proven to be adenocarcinoma of the frontal sinus. This case underscores the importance of thorough follow-up and investigation in patients presenting with recurrent or persistent symptoms following sinus surgery. This case highlighted the need for a high index of suspicion and comprehensive diagnostic workup.

摘要

额窦腺癌极为罕见。我们报告了一例伪装成内翻性乳头状瘤(IP)的原发性额窦腺癌。在此,我们回顾了额窦腺癌的各种临床表现、检查及治疗方法。一名48岁男性在因额窦内翻性乳头状瘤接受鼻内镜鼻窦手术后1个月出现鼻梁肿胀。肿胀逐渐增大并伴有持续的压迫症状,这使人们对先前确诊的诊断产生怀疑。影像学检查让我们处于恶性肿瘤与感染(骨髓炎)的治疗抉择关头。该病例的复杂性促使采用多学科团队方法,最终导致进行再次手术以重新评估。后来再次切除额窦肿瘤被证实为额窦腺癌。该病例强调了对鼻窦手术后出现复发或持续症状的患者进行全面随访和检查的重要性。此病例突出了高度怀疑指数和全面诊断检查的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0609/11425026/d461314d142c/cureus-0016-00000067878-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0609/11425026/e54e5e5ad65e/cureus-0016-00000067878-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0609/11425026/64a395fa1fd3/cureus-0016-00000067878-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0609/11425026/d461314d142c/cureus-0016-00000067878-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0609/11425026/e54e5e5ad65e/cureus-0016-00000067878-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0609/11425026/64a395fa1fd3/cureus-0016-00000067878-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0609/11425026/d461314d142c/cureus-0016-00000067878-i03.jpg

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本文引用的文献

1
Sinonasal Malignancies Involving the Frontal Sinus: A Mono-Institutional Experience of 84 Cases and Systematic Literature Review.累及额窦的鼻窦恶性肿瘤:单机构84例经验及系统文献综述
J Clin Med. 2023 Apr 28;12(9):3186. doi: 10.3390/jcm12093186.
2
Sinonasal malignancies: histopathological entities, regional involvement and long-term outcome.鼻窦恶性肿瘤:组织病理学实体、区域性累及和长期预后。
J Otolaryngol Head Neck Surg. 2023 Apr 28;52(1):36. doi: 10.1186/s40463-023-00627-8.
3
The Draf III procedure: A review of indications and techniques.
Draf III手术:适应症与技术综述。
World J Otorhinolaryngol Head Neck Surg. 2022 Mar 22;8(1):1-7. doi: 10.1002/wjo2.6. eCollection 2022 Mar.
4
Treatment of Sinonasal Adenocarcinoma: A Population-Based Prospective Cohort Study.鼻窦腺癌的治疗:一项基于人群的前瞻性队列研究。
J Neurol Surg B Skull Base. 2020 Dec;81(6):627-637. doi: 10.1055/s-0039-1694050. Epub 2019 Jul 30.
5
Squamous Cell Carcinoma Arising from Sinonasal Inverted Papilloma.来源于鼻腔鼻窦内翻性乳头状瘤的鳞状细胞癌。
AJNR Am J Neuroradiol. 2020 Jul;41(7):1156-1159. doi: 10.3174/ajnr.A6583. Epub 2020 May 28.
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Imaging Characteristics of Malignant Sinonasal Tumors.鼻窦恶性肿瘤的影像学特征
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7
Frontal Sinus Malignancies: A Population-Based Analysis of Incidence and Survival.额窦恶性肿瘤:基于人群的发病率和生存率分析
Otolaryngol Head Neck Surg. 2016 Apr;154(4):735-41. doi: 10.1177/0194599815621878. Epub 2015 Dec 23.
8
Sinonasal carcinoma associated with inverted papilloma: a report of 16 cases.与内翻性乳头状瘤相关的鼻窦癌:16 例报告。
J Craniomaxillofac Surg. 2012 Jun;40(4):e125-9. doi: 10.1016/j.jcms.2011.07.007. Epub 2011 Aug 19.