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摩洛哥智力残疾临床特征研究

Study of Clinical Characteristics of Intellectual Disability in Morocco.

作者信息

Bekkari Houda, Benmakhlouf Yousra, Nourouti Naima Ghailani, Barakat Amina, Mechita Mohcine Bennani

机构信息

All authors are with Intelligent Automation and BioMed Genomics Laboratory, Faculty of Sciences and Techniques of Tangier, at Abdelmalek Essaadi University, Morocco in Tangier, Morocco.

出版信息

Innov Clin Neurosci. 2024 Sep 1;21(7-9):10-14. eCollection 2024 Jul-Sep.

Abstract

OBJECTIVE

Intellectual disability (ID) is considered one of the most common human disorders characterized by significant deficits in cognition and functional and adaptive skills. The aims of this study were to describe the demographic and clinical features of a group of Moroccan individuals with ID living in the Tangier-Tetouan region.

DESIGN

This was a retro-prospective and descriptive exploratory monocentric study realized between November 2020 and August 2023. A total of 109 patients with ID were included. They were selected at four mental health centers in the Tangier-Tetouan region. Our data were treated and analyzed using the IBM SPSS version 26.

RESULTS

A male predominance of patients with ID was observed in our series (54.4% male vs. 42.6% female). The male-to-female ratio was 1.34. The mean±standard deviation (SD) age of our patients was 11.75±4.87 years, ranging from 1 to 35 years. The mean ages of mothers and fathers at the births of their children with ID were 28.36 and 35.6 years, respectively. Many co-occurring medical conditions were noted in our data (speech delay: 20.5%, concentration problems: 15.1%, hyperactivity: 11.1%, ambulation difficulties: 8.8%, aggressiveness: 8%, vision problems: 6.3%, epileptic seizures: 4%). The consanguinity rate was 26.9 percent.

CONCLUSION

ID associated with genetic causes was significantly correlated with the consanguinity rate in the Moroccan population.

摘要

目的

智力残疾(ID)被认为是最常见的人类疾病之一,其特征是认知、功能和适应技能存在显著缺陷。本研究的目的是描述居住在丹吉尔-得土安地区的一组摩洛哥智力残疾个体的人口统计学和临床特征。

设计

这是一项于2020年11月至2023年8月开展的回顾性、前瞻性和描述性探索性单中心研究。共纳入109例智力残疾患者。他们是在丹吉尔-得土安地区的四个心理健康中心挑选出来的。我们的数据使用IBM SPSS 26版进行处理和分析。

结果

在我们的研究系列中观察到智力残疾患者以男性为主(男性占54.4%,女性占42.6%)。男女比例为1.34。我们患者的平均年龄±标准差(SD)为11.75±4.87岁,年龄范围为1至35岁。孩子患有智力残疾的母亲和父亲在孩子出生时的平均年龄分别为28.36岁和35.6岁。我们的数据中记录了许多共病情况(语言发育迟缓:20.5%,注意力不集中问题:15.1%,多动:11.1%,行走困难:8.8%,攻击性:8%,视力问题:6.3%,癫痫发作:4%)。近亲结婚率为26.9%。

结论

在摩洛哥人群中,与遗传原因相关的智力残疾与近亲结婚率显著相关。

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本文引用的文献

1
Intellectual Disability in Morocco: A Pilot Study.摩洛哥的智力残疾:一项试点研究。
Innov Clin Neurosci. 2020 Oct 1;17(10-12):9-13. eCollection 2020 Oct-Dec.
2
What is a mental disorder? An exemplar-focused approach.什么是精神障碍?以范例为中心的方法。
Psychol Med. 2021 Apr;51(6):894-901. doi: 10.1017/S0033291721001185. Epub 2021 Apr 12.
4
Clinical Practice Guidelines for Assessment and Management of intellectual disability.智力残疾评估与管理临床实践指南
Indian J Psychiatry. 2019 Jan;61(Suppl 2):194-210. doi: 10.4103/psychiatry.IndianJPsychiatry_507_18.
5
Genetics of intellectual disability in consanguineous families.近亲家庭智力残疾的遗传学研究。
Mol Psychiatry. 2019 Jul;24(7):1027-1039. doi: 10.1038/s41380-017-0012-2. Epub 2018 Jan 4.
6
Yoga for epilepsy.用于癫痫治疗的瑜伽
Cochrane Database Syst Rev. 2017 Oct 5;10(10):CD001524. doi: 10.1002/14651858.CD001524.pub3.
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A comprehensive assessment of parental age and psychiatric disorders.全面评估父母年龄与精神障碍。
JAMA Psychiatry. 2014 Mar;71(3):301-9. doi: 10.1001/jamapsychiatry.2013.4081.

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