Sonoda Dai, Maruyama Raito, Kondo Yasuto, Naito Masahito, Mikubo Masashi, Shiomi Kazu, Satoh Yukitoshi
Department of Thoracic Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.
Department of Thoracic Surgery, Kitasato University Medical Center, 6-100 Arai, Kitamoto, Saitama, 364-08501, Japan.
Surg Today. 2025 Apr;55(4):588-599. doi: 10.1007/s00595-024-02938-3. Epub 2024 Sep 27.
Society is aging, and the proportion of older patients with lung cancer is increasing. However, the treatment choices and prognoses for older patients with cancer recurrence remain unclear. We retrospectively investigated the treatment choices and prognoses of older patients with recurrence.
We conducted a retrospective review of 1100 patients who underwent complete resection for non-small cell lung cancer at Kitasato University Hospital between 2004 and 2017. Patients of ≥75 years of age were defined as older patients, and the prognosis and prognostic factors of these patients upon recurrence were examined.
Among the 290 patients who developed recurrence, 106 experienced recurrence at an older age. The factors associated with survival after recurrence included sex, time to recurrence, number of recurrences, performance status at recurrence, and active treatment. As the age at recurrence increased, the proportion of patients who did not receive active treatment increased, as did the proportion for whom the reason was the patient's and family's preferences.
A considerable number of older patients who experience recurrence do not wish to receive active treatment. However, the prognosis can be improved by aggressive treatment for recurrence.
社会正在老龄化，老年肺癌患者的比例在增加。然而，癌症复发的老年患者的治疗选择和预后仍不明确。我们回顾性研究了老年复发患者的治疗选择和预后。
我们对2004年至2017年期间在北里大学医院接受非小细胞肺癌完全切除术的1100例患者进行了回顾性研究。年龄≥75岁的患者被定义为老年患者，并对这些患者复发后的预后和预后因素进行了检查。
在290例出现复发的患者中，106例在老年时复发。复发后生存相关因素包括性别、复发时间、复发次数、复发时的体能状态和积极治疗。随着复发年龄的增加，未接受积极治疗的患者比例增加，因患者及其家属意愿而未接受积极治疗的比例也增加。
相当数量的复发老年患者不希望接受积极治疗。然而，对复发进行积极治疗可以改善预后。
