Prentice R L, Marek P
Biometrics. 1979 Dec;35(4):861-7.
Two popular censored data rank tests were used to compare cancer incidence rates between dogs receiving bone marrow transplantation and control dogs. The logrank test gave a significance level of 0.01. In contrast, Gehan's generalized Wilcoxon test gave a significance level of 0.76. The statistics are displayed in a manner that shows how such contrasting significance levels can arise. The Gehan statistic is shown to be subject to a serious criticism that does not apply to other Wilcoxon generalizations. Further insight into the data is obtained using a time-dependent logrank test and the proportional hazards regression model.
使用两种常用的删失数据秩检验来比较接受骨髓移植的犬类与对照犬类之间的癌症发病率。对数秩检验给出的显著性水平为0.01。相比之下,Gehan广义威尔科克森检验给出的显著性水平为0.76。统计数据的呈现方式表明了这种截然不同的显著性水平是如何产生的。结果显示,Gehan统计量受到一种严重的批评,而这种批评并不适用于其他威尔科克森推广方法。使用时间相依对数秩检验和比例风险回归模型可进一步深入了解这些数据。