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在南非首次发现克里米亚-刚果出血热并确诊另外2例病例后的调查。

Investigations following initial recognition of Crimean-Congo haemorrhagic fever in South Africa and the diagnosis of 2 further cases.

作者信息

Swanepoel R, Shepherd A J, Leman P A, Shepherd S P

出版信息

S Afr Med J. 1985 Oct 26;68(9):638-41.

PMID:3933132
Abstract

Sera from 124 cattle herds were tested, and antibodies to Crimean-Congo haemorrhagic fever (CCHF) were found in 93 herds. The prevalence of antibodies was high in the interior of the country, in excess of 90% in some herds, but was less than 4% in cattle along the coast from Cape Town to East London. Only 17 out of 1109 (1,5%) human residents of 55 farms had antibodies to CCHF, while none of 164 veterinary research workers or 98 veterinarians engaged in farm animal practice had them. Specimens from 130 suspected cases of viral haemorrhagic fever were examined and CCHF was diagnosed only in the patient previously reported as the first case of the disease to be recognized in this country. A further 2 cases of CCHF were diagnosed by examining 318 specimens from patients with nonfatal febrile illness. Both patients had contact with livestock. Increasing awareness of the disease will probably lead to an increase in the number of cases diagnosed, but there are no grounds for concluding that the disease is on the increase.

摘要

对124个牛群的血清进行了检测,在93个牛群中发现了克里米亚-刚果出血热(CCHF)抗体。该国中部地区抗体流行率很高,一些牛群中超过90%,但从开普敦到东伦敦沿海地区的牛群中抗体流行率低于4%。55个农场的1109名居民中只有17人(1.5%)有CCHF抗体,而164名兽医研究人员或98名从事农场动物诊疗的兽医均无该抗体。对130例疑似病毒性出血热病例的标本进行了检测,仅在先前报告为本国首例确诊该疾病的患者中诊断出CCHF。通过检测318例非致命性发热疾病患者的标本又诊断出2例CCHF。两名患者均与家畜有接触。对该疾病认识的提高可能会导致确诊病例数增加,但没有理由得出该疾病正在增多的结论。

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