Shepherd A J, Swanepoel R, Shepherd S P, Leman P A, Blackburn N K, Hallett A F
S Afr Med J. 1985 Nov 9;68(10):733-6.
A nosocomial outbreak of Crimean-Congo haemorrhagic fever occurred in Tygerberg Hospital near Cape Town in September 1984 when 7 medical personnel became ill after admission of an index patient. The disease was fatal in the index and 1 secondary case, and was confirmed in the index and 6 secondary cases by isolation of the virus. An antibody response was demonstrated in the remaining patient, thought to be a tertiary case, but the fact that the patient received immune plasma therapy raises doubts about the validity of the diagnosis. The index case had contact with ticks and horses but his infection could not be related to a specific incident.
1984年9月，开普敦附近的泰格伯格医院发生了一起医院内克里米亚-刚果出血热暴发事件，一名首例患者入院后，7名医务人员患病。首例患者和1例二代病例死亡，通过病毒分离在首例患者和6例二代病例中确诊了该病。在其余被认为是三代病例的患者中检测到抗体反应，但该患者接受了免疫血浆治疗，这使得诊断的有效性受到质疑。首例患者曾接触过蜱虫和马匹，但其感染与某一特定事件并无关联。
