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登革出血热后的眼部和附属器表现。

Ocular and adnexal manifestations post dengue hemorrhagic fever.

机构信息

Department of Pediatric Ophthalmology, Strabismus and Neuro-Ophthalmology, CL Gupta Eye Institute, Ram Ganga Vihar, Phase II (Ext), Moradabad, Uttar Pradesh, India.

Department of Vitreoretina, CL Gupta Eye Institute, Ram Ganga Vihar, Phase II (Ext), Moradabad, Uttar Pradesh, India.

出版信息

Indian J Ophthalmol. 2024 Oct 1;72(10):1495-1500. doi: 10.4103/IJO.IJO_430_24. Epub 2024 Sep 27.

Abstract

OBJECTIVE

This study aims to present a case series detailing sight-threatening ocular and adnexal manifestations following dengue fever.

METHODS

A retrospective observational study was conducted, analyzing records of patients presenting with ocular manifestations post dengue fever at a tertiary eye care institute in Uttar Pradesh from October 2023 to November 2023. Demographic details, systemic comorbidities, and detailed ophthalmic examinations were recorded.

RESULTS

Fifteen eyes of 13 patients with dengue fever were studied. The mean age of presentation was 39.07 years, with a male predominance (84.61%). Systemic comorbidities were noted in 30.76% (diabetes mellitus) and 23.07% (hypertension) of patients. Thrombocytopenia was observed in 53.84% of patients, while 23.07% required blood transfusions, and 15.38% experienced systemic bleeding episodes. The majority of cases were unilateral (84.61%), with the best-corrected visual acuity of perception of light in 84.61% of cases. Diminution of vision was the most common presenting symptom (84.61%), followed by pain (53.84%), redness (38.46%), and watering (23.07%). Major ocular manifestations included panophthalmitis (26.07%), total ophthalmoplegia (26.07%), endogenous endophthalmitis (20%), central retinal artery occlusion (20%), retinal hemorrhage (20%), ischemic optic neuropathy (20%), orbital cellulitis (13.3%), proptosis (13.3%), retrobulbar hemorrhage (13.3%), retinal detachment (13.3%), and foveolitis (6.7%).

CONCLUSION

The diverse array of ocular and adnexal manifestations in dengue hemorrhagic fever may result in permanent visual loss, emphasizing the need for adequate treatment and timely intervention. The risk of sight-threatening complications underscores the importance of early screening by ophthalmologists and increased public awareness.

摘要

目的

本研究旨在介绍一系列病例,详细描述登革热后威胁视力的眼部和附属器表现。

方法

对 2023 年 10 月至 11 月在北方邦一家三级眼科医疗机构就诊的登革热后出现眼部表现的患者进行回顾性观察性研究。记录患者的人口统计学细节、合并的系统疾病和详细的眼科检查。

结果

研究了 13 例登革热患者的 15 只眼。发病时的平均年龄为 39.07 岁,男性居多(84.61%)。30.76%(糖尿病)和 23.07%(高血压)的患者存在合并系统疾病。53.84%的患者存在血小板减少,23.07%需要输血,15.38%出现全身出血事件。大多数病例为单侧(84.61%),84.61%的病例最佳矫正视力为光感。视力下降是最常见的首发症状(84.61%),其次是疼痛(53.84%)、眼红(38.46%)和流泪(23.07%)。主要的眼部表现包括全葡萄膜炎(26.07%)、完全眼肌麻痹(26.07%)、内源性眼内炎(20%)、视网膜中央动脉阻塞(20%)、视网膜出血(20%)、缺血性视神经病变(20%)、眶蜂窝织炎(13.3%)、眼球突出(13.3%)、球后出血(13.3%)、视网膜脱离(13.3%)和中心凹神经炎(6.7%)。

结论

登革出血热可引起多种多样的眼部和附属器表现,可能导致永久性视力丧失,强调需要充分治疗和及时干预。威胁视力的并发症风险突显了眼科医生早期筛查和提高公众认识的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cde2/11573032/95b7d6b357f2/IJO-72-1495-g001.jpg

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