Arora Payas, Bahuguna Nikita, Anand Jigisha, Semwal Prabhakar, Rai Nishant
Department of Biotechnology, Graphic Era (Deemed to Be University), Dehradun, 248002, Uttarakhand, India.
Department of Microbiology, Graphic Era (Deemed to Be University), Dehradun, 248002, Uttarakhand, India.
Z Naturforsch C J Biosci. 2024 Sep 30;80(7-8):297-315. doi: 10.1515/znc-2024-0130. Print 2025 Jul 28.
, known as the caterpillar fungus, constitutes an invaluable and irreplaceable part of traditional Chinese medicine (TCM) and is now gaining widespread global recognition and dedicated attention owing to both highly promising characteristics as well as grave dangers that are suggestive of an impending doom. possibly holds the key to the treatment of many human ailments with minimal side effects due to a wide array of biologically active chemical constituents. The powerful potential harbored by this fungus has led to a meteoric rise in its prices in the domestic and international markets which has caused the involvement of an increasing number of harvesters, traders, and buyers and unchecked overexploitation of this bioresource thus threatening its long-term survival in its natural habitat of the Himalayan region. This review focuses on the ethnopharmacology of and various aspects related to its conservation, such as natural distribution, sale and revenue, decline in population density, and conservational practices prevalent in the current scenario of fungal depletion. The paper concludes with a comprehensive evaluation of the discrete therapeutic capabilities possessed by , the mechanistic insights into the remarkable treatment of chronic ailments using the fungus or its derivatives, and a suggested strategic roadmap that may be adopted for fruitful conservation of this natural miracle.