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[先天性心脏病对神经发育的影响]

[The impact of congenital heart disease on neurodevelopment].

作者信息

Arroyo Hugo A, Foti Mariel

机构信息

Consultor, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Buenos Aires, Argentina. E-mail:

Servicio de Cardiología, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Buenos Aires, Argentina.

出版信息

Medicina (B Aires). 2024 Sep;84 Suppl 3:50-55.

Abstract

It is estimated that about 1 in 100 live births has a congenital heart disease (CHD). Cognitive deficit, academic difficulties, and behavioral abnormalities, in combination, represent the most common morbidity affecting quality of life in survivors with CHD. Developmental dysfunction results from a complex interaction between patient-specific factors such as genetic susceptibility, cardiac diagnosis, fetal development, and environmental factors such as preoperative events, supportive techniques during surgical repair, postoperative events, socioeconomic status. A comprehensive neurodevelopmental assessment in all children with CHD is critical to identify any need for intervention early and provide the support needed to optimize their long-term development.

摘要

据估计,每100例活产中约有1例患有先天性心脏病(CHD)。认知缺陷、学业困难和行为异常综合起来,是影响CHD幸存者生活质量的最常见发病情况。发育功能障碍是由患者特异性因素(如遗传易感性、心脏诊断、胎儿发育)与环境因素(如术前情况、手术修复期间的支持技术、术后情况、社会经济地位)之间复杂的相互作用导致的。对所有CHD患儿进行全面的神经发育评估,对于尽早确定是否需要干预并提供优化其长期发育所需的支持至关重要。

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