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[采用血管活性药物组合治疗脑血管源性器质性精神综合征]

[Therapy of organic psychosyndromes of cerebrovascular origin with a vasoactive drug combination].

作者信息

Lesch O M, Musalek M, Dietzel M, Grünberger J, Saletu B, Schjerve M, Walter H, Werner U, Zeiler K

出版信息

Wien Med Wochenschr. 1985 Sep 30;135(18):459-65.

PMID:3933188
Abstract

Concrete cross-sectional studies of the organic brain syndrome, carried out periodically, attempt to establish for the parameters evaluation of substrate damage--and different noopsychopathological rating-scales for the measurement of brain capacity impairment. Beyond the level of the purely correlative-statistical point of view of the relationship between parameter and score changes, demanding for a quantitative model which could provide not only a description, but also an explanation for such a relationship. The fact that there can only be a question here of a "quantitative causality" embracing non-specificity of toxic substances and relative to acute and chronic diffuse organic brain syndromes. It results, that quantitative causality meets the requirements of an exponential function model and that one can validate such models through correlative-statistical methods. This has already been carried out by Ball and Taylor.

摘要

定期进行的关于器质性脑综合征的具体横断面研究,试图建立用于评估底物损伤的参数——以及用于测量脑容量损害的不同神经精神病理学评定量表。除了从参数与分数变化之间关系的纯相关统计角度来看,还需要一个定量模型,该模型不仅可以描述这种关系,还能对其进行解释。这里只能涉及一种“定量因果关系”,它涵盖了有毒物质的非特异性以及相对于急性和慢性弥漫性器质性脑综合征的情况。结果是,定量因果关系符合指数函数模型的要求,并且可以通过相关统计方法验证此类模型。Ball和Taylor已经做到了这一点。

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