Zaloguev S N, Moroz A F, Antsiferova N G, Glatman L I, Popov V L
Zh Mikrobiol Epidemiol Immunobiol. 1985 Aug(8):3-7.
The experiment "Cytos-2" made it possible to reveal a certain increase in the antibiotic resistance of bacteria constituting the opportunistic pathogenic microflora of man (Staphylococcus, Escherichia coli and Pseudomonas aeruginosa) to oxacillin, erythromycin, colistin and kanamycin under the conditions of space flight. The electron-microscopic study of the postflight staphylococcal cultures revealed the thickening of the cell membrane in staphylococci. The conditions of the experiment did not affect the stability of the biochemical characteristics of P. aeruginosa cultures, as well as their virulence, immunogenic properties and type specificity.
“Cytos - 2”实验使得在太空飞行条件下,构成人类机会性致病微生物群(葡萄球菌、大肠杆菌和铜绿假单胞菌)的细菌对苯唑西林、红霉素、黏菌素和卡那霉素的抗生素耐药性出现一定程度的增加成为可能。对飞行后葡萄球菌培养物的电子显微镜研究显示,葡萄球菌的细胞膜增厚。实验条件并未影响铜绿假单胞菌培养物的生化特性稳定性,以及它们的毒力、免疫原性和型特异性。