Waweru F, Lewis S M
Acta Haematol. 1985;73(4):219-23. doi: 10.1159/000206345.
Essential thrombocythaemia was diagnosed in a series of 18 patients on the basis of platelet counts greater than 1,000 X 10(9)/1. Radionuclide studies have been carried out to distinguish thrombocythaemia as a primary disease from polycythaemia vera, myelofibrosis and chronic granulocytic leukaemia presenting with high platelet counts. These have included blood volume and spleen function, and radio-iron (52Fe) has been used to demonstrate the presence of extramedullary (splenic) erythropoiesis. The value of these investigations in distinguishing between the various myeloproliferative disorders associated with thrombocythaemia is illustrated.
根据血小板计数大于1000×10⁹/L，对18例患者诊断为原发性血小板增多症。已进行放射性核素研究，以将作为原发性疾病的血小板增多症与真性红细胞增多症、骨髓纤维化和血小板计数高的慢性粒细胞白血病区分开来。这些研究包括血容量和脾功能，并且已使用放射性铁（⁵²Fe）来证明髓外（脾）红细胞生成的存在。阐述了这些检查在区分与血小板增多症相关的各种骨髓增殖性疾病方面的价值。
