Revesz P, Carneskog J, Wadenvik H, Jarneborn L, Kutti J
Department of Medicine, Ostra Hospital, Göteborg, Sweden.
Eur J Haematol. 1993 Sep;51(3):141-3. doi: 10.1111/j.1600-0609.1993.tb00614.x.
By using gamma camera imaging the spleen size was determined in 33 consecutive patients with essential thrombocythaemia (ET) and in 33 consecutive patients with reactive thrombocytosis (RT). All ET patients were newly diagnosed and had not received myelosuppressive treatment prior to study; they all fulfilled the criteria for ET as established by the Polycythemia Vera Study Group. In both posterior and lateral projections, the spleen area in the group of ET patients was significantly larger than in the RT patients. The present study has shown that 39% of ET patients at diagnosis have splenic enlargement. Evaluation of spleen size is therefore a useful diagnostic test in patients presenting with unexplained thrombocytosis.
通过使用γ相机成像技术,对33例连续性原发性血小板增多症(ET)患者和33例连续性反应性血小板增多症(RT)患者的脾脏大小进行了测定。所有ET患者均为新诊断病例,在研究前未接受过骨髓抑制治疗;他们均符合真性红细胞增多症研究组制定的ET标准。在前后位和侧位投影中,ET患者组的脾脏面积均显著大于RT患者组。本研究表明,39%的ET患者在诊断时有脾脏肿大。因此,对不明原因血小板增多症患者进行脾脏大小评估是一项有用的诊断检查。