Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences (CAS), Beijing, P. R. China.
University of Chinese Academy of Sciences, Beijing, P. R. China.
Nat Commun. 2024 Sep 27;15(1):8409. doi: 10.1038/s41467-024-52567-0.
The olfactory system can generate unique sensory memories of various odorous molecules, guiding emotional and cognitive decisions. However, most existing electronic noses remain constrained to momentary concentration, failing to trigger specific memories for different smells. Here, we report an artificial olfactory memory system utilizing conductive metal-organic frameworks (Ce-HHTP) that integrates sensing and memory and exhibits short- and long-term memory responses to alcohols and aldehydes. Experiments and theoretical calculations show that distinct memories are derived from the specific combinations of Ce-HHTP with O atoms in different guest. An unmanned aircraft equipped with this system realized the sensory memories in established areas. Moreover, the fusion of portable detection boxes and wearable flexible electrodes demonstrated the immense potential in off-site pollution monitoring and health management. This work represents an artificial olfactory memory system with two specific sensory memories under simultaneous conditions, laying the foundation for bionic design with qualities of human olfactory memory.
嗅觉系统可以产生各种气味分子的独特感官记忆,指导情绪和认知决策。然而,大多数现有的电子鼻仍然局限于瞬时浓度,无法为不同的气味触发特定的记忆。在这里,我们报告了一种利用导电金属有机骨架(Ce-HHTP)的人工嗅觉记忆系统,该系统具有传感和记忆功能,对醇和醛具有短期和长期记忆响应。实验和理论计算表明,不同的记忆来自于 Ce-HHTP 与不同客体中 O 原子的特定组合。一架配备该系统的无人机实现了在已建立区域的感官记忆。此外,便携式检测盒和可穿戴柔性电极的融合展示了在现场外污染监测和健康管理方面的巨大潜力。这项工作代表了一种在同时条件下具有两种特定感官记忆的人工嗅觉记忆系统,为具有人类嗅觉记忆品质的仿生设计奠定了基础。